Evidence map›Paper›PMID 41107205›Full record

ArticleThe Laryngoscope2026

Nebulized Lidocaine Through a Channeled Endoscope for Office Laryngology Procedures.

Dylan Z Erwin, Abigail N Kennedy, Matthew Y Liu, Laura M Dominguez, C Blake Simpson, Zao Mike Yang

Abstract readComparative Study
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dylan Z ErwinDepartment of Otolaryngology - Head & Neck Surgery, University of Texas Health San Antonio, San Antonio, Texas, USA.
Abigail N KennedyJoe R. & Teresa Lozano Long School of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.
Matthew Y LiuDepartment of Otolaryngology - Head & Neck Surgery, University of Texas Health San Antonio, San Antonio, Texas, USA.ORCID 0000-0001-9114-6571
Laura M DominguezENT Southlake, Centers for Advanced ENT Care, Southlake, Texas, USA.ORCID 0000-0002-0122-276X
C Blake SimpsonDepartment of Otolaryngology - Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Zao Mike YangDepartment of Otolaryngology - Head & Neck Surgery, University of Texas Health San Antonio, San Antonio, Texas, USA.ORCID 0000-0003-0701-3341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study sought to compare topical lidocaine delivered through a channeled endoscope versus traditional anesthetic methods for office laryngology procedures.

methodsA single-institution prospective, crossover study of adult patients undergoing office laryngology procedures from February 2023 to February 2024 was conducted. Patient-reported outcomes for procedural tolerance and anesthetic preference were compared between the investigational method of channel-nebulized lidocaine versus control anesthetic delivery (trans-tracheal or drip catheter), with each patient serving as his/her own control.

resultsTwenty-two subjects were included in the study. Control topical anesthesia included: 13 (59.1%) trans-tracheal and 9 (40.9%) drip catheter. On bivariate analysis, the use of channel-nebulized lidocaine was associated with reduced lidocaine dosage (0.4 vs. 1.7 mL, p < 0.001), increased anesthesia delivery time (335 vs. 119 s, p < 0.001), and increased total procedure time (543 vs. 321 s, p < 0.001). No significant differences in anesthetic delivery time or total procedure time were observed when comparing channel-nebulized delivery with drip catheter. Discomfort during lidocaine administration (p < 0.001) and cough/gag during lidocaine administration (p < 0.001) were significantly lower with channel-nebulized lidocaine. Multiple linear regression revealed these improvements were not significantly influenced by indication for procedure, years undergoing procedures, or control method of anesthesia. A majority (63.6%) of patients preferred channel-nebulized lidocaine.

conclusionTopical laryngeal anesthesia for office laryngology procedures can be challenging due to patient tolerance. Nebulized lidocaine delivered through an endoscopic working channel may improve patient tolerance and reduce lidocaine dosage but may be associated with longer procedure time. LEVEL OF EVIDENCE: 3:

Indexed as

Ambulatory Surgical ProceduresAnesthesia, LocalAnesthetics, LocalEndoscopesLaryngoscopyLidocaineAdultAgedCross-Over StudiesFemaleHumansMaleMiddle AgedNebulizers and VaporizersProspective StudiesAnesthetics, LocalLidocainelaryngologynebulized lidocaineoffice‐based procedurespatient preferencestopical anesthesia

Identifiers

PMID41107205
PMCPMC12913739

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.