ArticleJACC. Case reports2025
Severe Aortic Regurgitation Due to Quadricuspid Aortic Valve.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
case summaryQuadricuspid aortic valve is a rare congenital malformation with prevalence of <0.05%, often manifesting in mid- to late adulthood with aortic regurgitation (AR). We present a case of a 60-year-old man with chronic severe AR due to phenotype F quadricuspid aortic valve and mild to moderate functional mitral regurgitation. Cardiac catheterization revealed multivessel coronary artery disease. The patient underwent successful surgical aortic valve replacement with a bioprosthesis and 2-vessel coronary artery bypass graft surgery. Echocardiography at 1-month follow-up showed improved left ventricular volumes, normal aortic bioprosthesis, and trivial mitral regurgitation. This case highlights the role of echocardiography in diagnosing quadricuspid aortic valve and guiding management. TAKE-HOME MESSAGES: Quadricuspid aortic valve is a rare cause of AR that can be readily diagnosed on echocardiography. Surgical aortic valve replacement is an effective treatment for severe symptomatic AR due to quadricuspid aortic valve.
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