ReviewMolecular cell2025
Orchestration of plant PRR- and NLR-mediated immunity: Protein kinases and beyond.
Review in Molecular cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- A domestication-selected CIPK-MYB-HAK module improves salt tolerance in modern maize.Nature plants · 2026Article
- Systemic acquired resistance: an emerging role for jasmonates in local signal biogenesis, translocation and distal signal decoding.The New phytologist · 2026Review
- Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation.Journal of integrative plant biology · 2026Review
- A fellowship of the rings in plant defence.Nature · 2026Article
- Article
- De-repression of protein phosphatase 5 by the chaperone organizer HOP1 activates plant NLR immunity.Nature plants · 2026Article
- Functional Dissection of a Wheat NLR Protein Reveals a Minimal Active Region and Key Regulatory Sites for Immune Signalling.Molecular plant pathology · 2026Article
- TaELP2 Interacts With TaDCL1 and Negatively Regulates Wheat Resistance Against Stripe Rust.Molecular plant pathology · 2026Article
- Structural dynamics, pathogenic mechanisms, and therapeutic targeting of the NLRP3 inflammasome in lupus nephritis.Frontiers in immunology · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The plant immune system senses infections primarily through two branches of immune receptors: cell surface-resident pattern-recognition receptors (PRRs) and intracellular NOD-like receptors (NLRs). Although distinct in perception and activation, PRR and NLR signaling are interconnected and mutually regulated. A major class of PRRs, receptor kinases (RKs), often activate intracellular kinases, including receptor-like cytoplasmic kinases (RLCKs) and mitogen-activated protein kinases (MAPKs). Some RLCKs act as decoys, activating NLRs upon pathogen effector recognition. Recent advances expand the repertoire of kinases, including RKs, tandem kinase proteins, and calcium-dependent protein kinases, by directly activating or suppressing NLRs through phosphorylation. Furthermore, PRR-regulated RKs and MAPKs play critical roles in restraining NLR activity to maintain immune homeostasis. In response to pathogen perturbations, plants mobilize backup surveillance mechanisms involving RKs and RLCKs to derepress NLR immunity. This review highlights recent advances in the dynamic interplay between PRR and NLR signaling, focusing on protein kinases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.