ArticleDrug and alcohol dependence2025
Cross sectional multi-sample study of nonfatal overdose in adolescents and young adults in the fentanyl era.
Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ready, willing, and able: understanding opioid overdose preparedness among college students in the southwestern United States.Frontiers in public health · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
16 authors.
Funding
Abstract
introductionOverdose deaths disproportionately increased among adolescents and young adults (AYA) between 2019 and 2022, despite declining substance use. We examined the prevalence of nonfatal overdose and characteristics associated with overdose history in AYA.
methodsAYA enrolled between 2020 and 2023 in five opioid use disorder prevention studies in child welfare, healthcare, and legal settings from six states were included in this analysis. Nonfatal overdose history, demographic, and clinical characteristics were assessed at baseline. Across studies, overdose history was assessed with slight variations in wording, but most other measures were standardized. Odds ratios (OR) of lifetime overdose were calculated with logistic regression for each risk factor with demographic control variables (age, sex, race) included as covariates, and reported separately by sample.
resultsSample sizes ranged from 137 to 929 (total N = 1856). Characteristics across samples ranged from M = 16.2-26.4 years for age, and 11.7-91.9 % for female sex. For race, samples ranged from 35 % to 89.4 % White and 17.3-89.4 % Black. History of nonfatal overdose ranged from 6.6 % to 41.4 %. Statistically significant characteristics associated with overdose history in all samples included history of opioid misuse (ORs ranging from 1.98 to 6.73) and family members with a substance use problem (ORs range from 1.27 to 2.05). Frequent and early onset alcohol and cannabis use was also associated with overdose history in several samples.
conclusionsOverdose prevention interventions for AYA should include a focus on AYA who misuse opioids and families with a history of substance use problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.