ReviewCytokine & growth factor reviews2025
Arteriolar angiogenesis: implications in anti-angiogenic immunotherapy for pancreatic cancers.
Review in Cytokine & growth factor reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endothelial-to-mesenchymal transition and vasculogenic mimicry in tumor vascular plasticity: a comparative bibliometric analysis and mechanistic framework.Frontiers in oncology · 2026Pooled it
- CAR-macrophages: a new chapter in cancer immunotherapy.Acta biochimica et biophysica Sinica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Angiogenesis, the newly formed blood vessels from preexistent ones, is essential for the progression and potential resolution of diseases. Here we introduce a view of arteriolar angiogenesis (the growth of new small arteries), and define a concept that molecular signaling balance between pro- and anti-angiogenic signaling determines angiogenic phenotype. We discuss VEGF and CXCL12 signaling pathways in vascular endothelial cells essential for arteriolar angiogenesis, which is potentially regulated by PKD1-mediated Notch1-CD36 signaling, emphasizing the function of arteriolar angiogenesis as a vascular niche/microenvironment under pathological conditions. We delineate implications of arteriolar angiogenesis in cancer stem cell development and anti-angiogenic immunotherapeutic strategies, highlighting anti-angiogenic strategy in combination with immune checkpoint blockade in pancreatic cancers. In summary, this review article seeks to develop the concept of arteriolar angiogenesis and yield insights into developing novel vascular targeting and immune therapies to cure cancers and cardiovascular and neurovascular diseases manifested with abnormal angiogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.