Evidence map›Paper›PMID 41105966›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Variations in Ovarian Cancer Survival Rates: Investigating Equity and Prognostic Factors Throughout Nova Scotia.

Sarah Scruton, George Kephart, Lana Saciragic, Robin Urquhart

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Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sarah ScrutonCancer Outcomes Research Program, Department of Surgery, Nova Scotia Health Authority, Halifax, NS, Canada.ORCID 0009-0006-1260-2043
George KephartDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.
Lana SaciragicDepartment of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS, Canada.
Robin UrquhartCancer Outcomes Research Program, Department of Surgery, Nova Scotia Health Authority, Halifax, NS, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionThere is large inter- and intra-country variability in ovarian cancer outcomes. Individuals diagnosed with advanced stage cancer in Nova Scotia have a 3-year net survival of 31.9%, the lowest in the country. This study aimed to identify factors impacting survival, and to investigate evidence of inequities in survival from the point of diagnosis moving forward.MethodsThis population-based retrospective study included all women diagnosed with ovarian cancer in Nova Scotia from Jan 1, 2007, to Dec 31, 2016. Administrative health data were linked to gather individual, tumor, and health system characteristics. Both prognostic and equity factors potentially contributing to variations and inequities in survival were assessed using descriptive and time to event techniques.ResultsThis study found no regional differences in survival across Nova Scotia. It revealed that disparities in equity factors do not appear to be significantly associated with survival at the time of diagnosis moving forward. Instead, survival variations were attributed to legitimate prognostic factors, such as cancer stage, subtype, comorbidities, and frailty. However, notable inequities were identified between socioeconomic status and prognostic factors that may contribute to poor survival upstream, rather than at the time of diagnosis.ConclusionThough inequities do not appear to directly contribute to differences in ovarian cancer survival at the time of diagnosis, they may influence outcomes by increasing the development of prognostic factors that lead to poorer survival. Future research should capture equity factors not found in administrative data and begin making comparisons between other jurisdictions to determine why survival rates vary worldwide.

Indexed as

Healthcare DisparitiesOvarian NeoplasmsAdultAgedFemaleHumansMiddle AgedNova ScotiaPrognosisRetrospective StudiesSocioeconomic FactorsSurvival Rateadministrative datainequitiesovarian cancersurvivaltime-to-event

Identifiers

PMID41105966
PMCPMC12541166

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