Evidence map›Paper›PMID 41105947›Full record

ArticleJournal of medical Internet research2025

Challenges and Recommendations for Electronic Health Records Data Extraction and Preparation for Dynamic Prediction Modeling in Hospitalized Patients: Practical Guide and Tutorial.

Elena Albu, Shan Gao, Pieter Stijnen, Frank E Rademakers, Bas Ct van Bussel, Taya Collyer, Tina Hernandez-Boussard, Laure Wynants, Ben Van Calster

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena AlbuDepartment of Development & Regeneration, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-2602-0918
Shan GaoDepartment of Development & Regeneration, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-0871-1694
Pieter StijnenManagement Information Reporting Department, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-3047-6902
Frank E RademakersFaculty of Medicine, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-7786-4179
Bas Ct van BusselCare and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0003-1621-7848
Taya CollyerPeninsula Clinical School, Central Clinical School, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-8612-1724
Tina Hernandez-BoussardDepartment of Medicine, Stanford University, Stanford, CA, United States.ORCID https://orcid.org/0000-0001-6553-3455
Laure WynantsDepartment of Development & Regeneration, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-3037-122X
Ben Van CalsterDepartment of Development & Regeneration, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-1613-7450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dynamic predictive modeling using electronic health record data has gained significant attention in recent years. The reliability and trustworthiness of such models depend heavily on the quality of the underlying data, which is, in part, determined by the stages preceding the model development: data extraction from electronic health record systems and data preparation. In this paper, we identified over 40 challenges encountered during these stages and provided actionable recommendations for addressing them. These challenges are organized into 4 categories: cohort definition, outcome definition, feature engineering, and data cleaning. This comprehensive list serves as a practical guide for data extraction engineers and researchers, promoting best practices and improving the quality and real-world applicability of dynamic prediction models in clinical settings.

Indexed as

Electronic Health RecordsHospitalizationInformation Storage and RetrievalHumansdata extractiondata preparationdynamic prediction modelsEHR dataelectronic health recordsETLextract, transform, load

Identifiers

PMID41105947
PMCPMC12579287

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.