Evidence map›Paper›PMID 41105939›Full record

ArticleJMIR research protocols2025

Community-Engaged Approach to Increase Physical Activity Among Black Individuals With Colorectal Cancer: Protocol for a Feasibility Randomized Controlled Trial of the Physical Activity Centers Empowerment Study.

Rachel Hirschey, Jingle Xu, Nathaniel Woodard, Paulette Duggins, Deirdre F Lea, John L Milner, Karia Coleman, Ashley Leak Bryant, Hanna K Sanoff, Tammy Triglianos and 7 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06411756 (Physical Activity Intervention Co-created and Tested With African American Colorectal Cancer Survivors), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06411756 nacompletednot on this map

Physical Activity Intervention Co-created and Tested With African American Colorectal Cancer Survivors

TypeinterventionalSponsorUNC Lineberger Comprehensive Cancer CenterRan2024 to 2026Enrolled21ConditionsColorectal NeoplasmsArmsNarrative videos, A Fitbit activity tracker, Daily text message, Monthly Zoom meeting, Website access
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rachel HirscheySchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-8358-0650
Jingle XuSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0003-1287-8243
Nathaniel WoodardDepartment of Community Health and Health Behavior, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, United States.ORCID 0000-0002-9860-5870
Paulette DugginsStiving to Hold Accountability in Research Equity Community Advisory Board, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0009-0004-9879-5557
Deirdre F LeaStiving to Hold Accountability in Research Equity Community Advisory Board, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-9229-2295
John L MilnerStiving to Hold Accountability in Research Equity Community Advisory Board, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-6358-833X
Karia ColemanStiving to Hold Accountability in Research Equity Community Advisory Board, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-5347-4873
Ashley Leak BryantSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0003-1178-1781
Hanna K SanoffLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-8679-4486
Tammy TriglianosSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0009-0007-2869-295X
Baiming ZouDepartment of Biostatistics, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-7879-9460
Natasha Renee BurseSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-4381-1714
Rebecca L HooverMark and Robyn Jones College of Nursing, Montana State University, Bozeman, MT, United States.ORCID 0000-0003-0695-6348
Jennifer LeemanSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0003-3130-8297
Stephanie B WheelerLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-3399-9047
Claudio L BattagliniLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0002-4224-6477
Carmina G ValleLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0003-1985-2409

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JAMES E BEAR · 1985 to 2026
$201.5M
Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
Robust Computational and Data Analytic Tools for In-depth Understanding Postoperative Pain Mechanism with Enhanced Pain Management and Clinical Decision MakingR01LM014407 · NLM · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Baiming Zou · 2024 to 2026
$1.4M
Physical activity intervention co-created and pilot tested with African American Colorectal Cancer SurvivorsK23MD015719 · NIMHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HIRSCHEY, RACHEL · 2021 to 2025
$795k
Understanding Quality of Life and Physical Activity in Black Breast Cancer SurvivorsK00CA253762 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BURSE, NATASHA RENEE · 2022 to 2025
$343k
The processes through which prostate cancer survivors and their partners adopt and maintain a healthy diet during prostate cancer survivorshipF31NR021241 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI XU, JINGLE · 2024 to 2025
$80k
Incidence and Time on Onset of Cardiovascular Risk Factors and Cardiovascular Disease in Adult Survivors of Adolescent and Young Adult Cancer and Association with ExerciseF31CA275332 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOOVER, BECKY LEIGH · 2023 to 2024
$59k
NCI NIH HHS F31 CA275332NCI NIH HHS K00 CA253762NCI NIH HHS P30 CA016086NCI NIH HHS T32 CA116339NIMHD NIH HHS K23 MD015719NINR NIH HHS F31 NR021241NLM NIH HHS R01 LM014407
6 · The paper itself

Abstract

backgroundBlack individuals are more likely to die from colorectal cancer (CRC) and experience more treatment-related side effects compared to White individuals. Physical activity (PA) has been associated with decreased side effects, improved CRC treatment completion rates and responses, and survival. However, Black survivors of CRC are 60% less likely to engage in PA than White survivors. The Physical Activity Centers Empowerment (PACE) study is testing an intervention specifically designed to increase PA among Black individuals diagnosed with CRC.

objectiveThis study outlines the protocol for a randomized controlled trial. The study aims to test the feasibility of PACE and will use the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework.

methodsThe PACE study was developed in partnership with a community advisory board consisting of Black cancer advocates and survivors of cancer. The study aims to recruit 72 participants aged >18 years from North Carolina who have been diagnosed with CRC. These participants will be randomized in a 1:1 ratio to an intervention or control group. During the 12-week intervention, all participants will receive a wearable activity tracker and informational materials from the American College of Sports Medicine's "Moving through Cancer" program. The intervention group will also receive additional PACE theory-guided intervention components, including personalized daily adaptive step goals, access to the PACE video library, and optional video chat meetings for PA support. Data will be collected at 3 time points: baseline, after the intervention (3 months), and 6 months after the intervention (9 months). Using the RE-AIM framework, the study aims to evaluate the intervention's reach, effectiveness, acceptability, implementation, and maintenance.

resultsThe National Institute on Minority Health and Health Disparities funded this study in 2021. Study enrollment began in August 2024 and is anticipated to conclude in December 2024.

conclusionsThis study will advance our understanding of effective behavioral strategies to increase PA and help advance the use of PA as a form of complementary cancer treatment, with the aim of improving health outcomes for Black survivors of CRC.

trial registrationClinicalTrials.gov NCT06411756; https://clinicaltrials.gov/study/NCT06411756. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/65804.

Indexed as

Black or African AmericanColorectal NeoplasmsExerciseHealth PromotionAdultCancer SurvivorsEmpowermentFeasibility StudiesFemaleHumansMaleMiddle AgedNorth CarolinaRandomized Controlled Trials as TopicAfrican Americancolorectal cancercommunity-based participatory researchdisparitiesphysical activity

Identifiers

PMID41105939
PMCPMC12579295

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.