Evidence map›Paper›PMID 41105938›Full record

Trial reportJournal of medical Internet research2025

Evaluating a Mobile Health Intervention (GUIDE App) for First Responders, Military Personnel, and Veterans: Randomized Controlled Trial.

Morgan K Dunphy, Heather J Nuske

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06336967 (A Randomized Controlled Trial of a Wellness App for First Responders, Military Personnel and Veterans), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06336967 nacompletednot on this map

A Randomized Controlled Trial of a Wellness App for First Responders, Military Personnel and Veterans

TypeinterventionalSponsorUniversity of PennsylvaniaRan2024 to 2024Enrolled115ConditionsMental Health WellnessArmsGUIDE
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Morgan K Dunphy *Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0009-0007-3701-2979
Heather J Nuske *Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-6618-3768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFirst responders, military personnel, and veterans face disproportionate risk for mental health and wellness issues. Stigma and confidentiality are common barriers to traditional services. Mobile health interventions offer anonymous, convenient, and cost-effective alternatives.

objectiveThis study aimed to evaluate the impact of GUIDE, a mobile health intervention, on wellness, emotional well-being, mental health, social connectedness, and personal growth in first responders, military personnel, and veterans.

methodsIn this unblinded, randomized, waitlist-controlled trial, 115 participants recruited online and offline were virtually enrolled and allocated into 3 groups: GUIDE with financial incentives (GUIDE+incentives, n=37), GUIDE-only (n=39), or waitlist control (n=39). Web-based surveys assessed baseline and posttrial wellness (PERMA [Positive Emotion, Engagement, Relationships, Meaning, Accomplishment] Overall, World Health Organization 5-item Well-being Index, Personal Well-being Score, and PERMA Health), emotional well-being (PERMA Positive Emotion, Negative Emotion, and Happiness; and Difficulties in Emotion Regulation Scale), mental health (Patient Health Questionnaire-8 [depression] and Generalized Anxiety Disorder-7 [anxiety]), social connectedness (PERMA Relationships and Loneliness), and personal growth (PERMA Accomplishment, Meaning, and Engagement). App engagement and technical merit were also evaluated.

resultsAmong the participants, 93.0% (107/115) completed the posttrial assessment and were included in the main analysis. In repeated measures ANOVAs, there were no significant group×time interactions for wellness (ηp

conclusionsGUIDE is a feasible and appropriate intervention with the potential to improve the mental health and well-being of first responders, veterans, and military personnel. Financial incentives increased engagement with peer-support features but did not lead to significant improvements over waitlist controls. Future research should assess whether improvements are sustained in the long term.

trial registrationClinicalTrials.gov NCT06336967; https://clinicaltrials.gov/study/NCT06336967.

Indexed as

Military PersonnelMobile ApplicationsVeteransAdultFemaleHumansMaleMental HealthMiddle AgedSurveys and QuestionnairesTelemedicineanxietydepressiondigital healthfirst respondersmHealthmilitarymobile healthrandomized trialresilienceveteranswellness

Identifiers

PMID41105938
PMCPMC12579301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.