ArticlePLOS digital health2025
On the road to vision zero: How unit-dose dispensing systems and health-IT are transforming clinical practices.
Article in PLOS digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study investigates real-world prescribing patterns and validation workflows linked to the implementation of a Unit-Dose Dispensing System (UDDS) within a digital medication management framework. The overall goal is to enhance medication safety, minimize errors, and improve clinical efficiency and workflow processes. Retrospective analysis of prescription data from the Electronic Medication System (EMS) in 2023 at a large tertiary care teaching hospital focused on physicians` prescribing patterns, drug compatibility with UDDS, and challenges faced by pharmacists during validation. Interactive dashboards provided real-time insights into prescription types, volumes, timing, and pharmacist validation rates. Of the 4.7 million doses prescribed in 2023, 64% were UDDS-compatible, highlighting its strong potential to streamline workflows and reduce nursing workload on the wards. Dashboard analysis revealed a clear alignment between peak prescribing times and UDDS production schedules, indicating effective synchronization between clinical and logistical workflows. Notably, an average of 631.6 blister-packable doses per day remained unvalidated by clinical pharmacists due to contraindications, dosage discrepancies, or duplicate prescriptions, emphasizing the need for enhanced health-IT support to address these gaps. UDDS combined with interactive dashboards enables targeted filtering and rapid identification of trends and gaps in pharmacotherapy. Integrating UDDS into a digital medication management framework offers significant potential to improve patient safety and operational efficiency. Key challenges in implementing UDDS into routine clinical practice were identified. Adhering to prescription submission cut-off times is essential to ensure UDDS effectiveness. Tailoring UDDS workflows and interactive dashboards to department-specific needs can further improve medication safety, strengthen pharmacists' oversight, and support the long-term sustainability of safe and efficient medication practices.
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Registered trials
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