ArticlePloS one2025
Antimicrobial stewardship programs and antibiotic use in Africa: A systematic review and meta-analysis protocol.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Factors influencing antibiotic prescription for respiratory tract infections among prescribers in Jinja City, Uganda: a qualitative study.BMC pulmonary medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance (AMR) is a significant public health crisis, particularly in Africa where infectious disease burdens are high. While antimicrobial stewardship programs (ASPs) are a key intervention, a comprehensive synthesis of their impact on antibiotic use in this context is lacking.
objectiveThis systematic review and meta-analysis aims to synthesize current evidence regarding the association between ASPs and antibiotic use in Africa.
methodsMEDLINE (PubMed), Embase, CINAHL, Web of Science, and regional databases including african journals online and WHO global index medicus will be searched systematically. Original studies of the association of ASPs with antimicrobial consumption across healthcare settings will be included while Animal and environmental studies will be excluded. Two independent reviewers will screen articles, extract data, and assess quality using the Effective Public Health Practice Project (EPHPP) quality assessment tool. The main outcome measures will be proportion of patients receiving anantibiotic prescription and defined daily doses per 100 patient days. The pooled association of targeted ASPs with antimicrobial consumption will be be measured using multilevel random-effects models. EXPECTED OUTCOMES: This systematic review and meta-analysis is expected to provide valuable, pooled evidence on the effectiveness of ASPs in reducing antimicrobial consumption in Africa. The findings will inform and call for evidence based interventions by governments and Non-Governmental Organizations (NGOs) to combat AMR in resource limited settings. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD420251003018.
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