ReviewPain practice : the official journal of World Institute of Pain2025
Analyzing the Landscape of Botulinum Toxin Research: A Bibliometric Study of Publication Performance and Emerging Trends.
Review in Pain practice : the official journal of World Institute of Pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Highly Cited Research on Botulinum Toxin: A Bibliometric Analysis of Clinical Trends, Influential Evidence, and Healthcare-Relevant Applications (1991-2022).Healthcare (Basel, Switzerland) · 2026Review
- Highly Cited Dental Implant Research: A Bibliometric Analysis of Publication Patterns and Research Themes.Healthcare (Basel, Switzerland) · 2026Review
- Analyzing the Landscape of Botulinum Toxin Research: A Bibliometric Study of Publication Performance and Emerging Trends.Pain practice : the official journal of World Institute of Pain · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to conduct a comprehensive bibliometric analysis of the global scientific literature on botulinum toxin from 1991 to 2024, evaluating publication performance, citation impact, and emerging research foci.
methodsData were retrieved from the Science Citation Index Expanded (SCI-EXPANDED) of the Web of Science Core Collection. The data extraction procedure included titles, abstracts, author keywords, and Keywords Plus. Publication and citation metrics (TP, IP, CP, FP, RP, SP, CPP
resultsA total of 25,522 relevant documents were identified, with a marked increase in publications over time. The United States led in publication output and citation impact, followed by Germany, the United Kingdom, and China. Notably, countries such as South Korea, Italy, France, and Turkey showed a recent surge in output. Allergan Pharmaceutical Inc. demonstrated the highest citation performance among all institutions. Three primary research themes were identified: clinical indications, administration and formulations, and evaluation of efficacy and safety. The findings also highlighted increased international and interdisciplinary collaborations over time, as well as growing interest in surgical and aesthetic applications.
conclusionBotulinum toxin research has grown significantly in both scope and volume over the past three decades, with notable contributions from both academic and industrial institutions. Understanding global research performance and thematic trends provides a foundation for future clinical, academic, and commercial development in the field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.