Evidence map›Paper›PMID 41105434›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Temporal Trends in Outcomes and Predictors of Length of Stay following Lung Cancer Resection over 10 Years with Enhanced Recovery After Surgery.

Lauren Kari Dixon, David Messenger, Lesley Wood, Neil Rasburn, Douglas West, Eveline Internullo, Rakesh Krishnadas, Igor Saftic, Stylianos Gaitanakis, Laura Socci and 3 more

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Robotic surgery for pulmonary sequestration: interpreting early advantages.General thoracic and cardiovascular surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lauren Kari DixonThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
David MessengerColorectal Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Lesley WoodDatabase Manager, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Neil RasburnAnaesthesia, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Douglas WestThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Eveline InternulloThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Rakesh KrishnadasThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Igor SafticThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Stylianos GaitanakisThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Laura SocciThoracic Surgery, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Michelle BrackERAS Specialist Nurse, University Hospitals Bristol and Weston, Bristol, United Kingdom.
Timothy BatchelorThoracic Surgery, St Bartholomew's Hospital, London, United Kingdom.
Natasha JoshiAnaesthesia, University Hospitals Bristol and Weston, Bristol, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEnhanced Recovery After Surgery aims to accelerate recovery, with length of stay as a key metric. This study assessed temporal trends in short-term outcomes within a maturing programme and identified factors associated with increased hospital stay.

methodsData were prospectively collected for consecutive patients undergoing lung cancer resection following a 14-step protocol between 2013 and 2023. Primary outcome was length of stay. Secondary outcomes included 30-day mortality, morbidity, re-admission, and reoperation rates. Predictors of length of stay were analysed using linear regression.

resultsWe included 2192 patients; procedures included lobectomy (61%), wedge resection (23%), segmentectomy (10%), pneumonectomy (3.5%), and bi-lobectomy (2.7%), Video-assisted thoracoscopic surgery was used in 80% of cases. Median length of stay decreased from 5 to 4 days (p < 0.001), while protocol adherence increased from 10/14 to 12/14 (p = 0.01). In-hospital mortality (2.9% to 1.0%, p < 0.001) and major-morbidity (12.2% to 5.6%, p < 0.001) both declined. In multivariable linear regression, factors associated with longer stay included age (β = 0.17, CI 0.13-0.20, p < 0.001), higher American Society of Anesthesiologists score (β = 1.12, CI 1.04-2.2, p = 0.02), open surgery (β = 1.0, CI 0.17-2.2, p = 0.043), thoracoscopic-to-open converted surgery (β = 1.49, CI 0.96-1.9, p = 0.03) and intensive care (β = 3.4, CI 2.5-4.3, p < 0.001). Protective factors were early mobilisation (β=-0.90, CI -1.9-0.33, p = 0.005) and opioid avoidance (β=-0.72, CI -2.4-0.99, p = 0.038).

conclusionsSustained use of an Enhanced Recovery After Surgery programme was associated with shorter hospitalisation and reduced morbidity. Factors associated with length of stay can identify patients at risk of delayed recovery and prioritise elements for optimisation within recovery pathways.

Indexed as

ERASlobectomylung cancerthoracic surgeryVATS

Identifiers

PMID41105434
PMCPMC12548365

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.