Evidence map›Paper›PMID 41105350›Full record

ArticleInsights into imaging2025

Predicting pathological subtypes of pure ground-glass nodules using Swin Transformer deep learning model.

Yanhua Wen, Menna Allah Mahmoud, Wensheng Wu, Huicong Chen, Yingying Zhang, Xiaohuan Pan, Yubao Guan

Abstract read
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Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yanhua Wen *Department of Medical Imaging, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Menna Allah Mahmoud *Department of Medical Imaging, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wensheng WuDepartment of Medical Imaging, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Huicong ChenGuangzhou Medical University, Guangzhou, China.
Yingying ZhangGeneral Hospital of the Southern Theatre of the Chinese People's Liberation Army, Guangzhou, China.
Xiaohuan PanDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yubao GuanDepartment of Medical Imaging, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. yubaoguan@163.com.ORCID http://orcid.org/0000-0003-0171-3662

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 82272080
6 · The paper itself

Abstract

objectivesTo explore the diagnostic value of a multi-classification model based on deep learning in distinguishing the pathological subtypes of lung adenocarcinoma or glandular prodromal lesions with pure ground-glass nodules (pGGN) on CT. MATERIALS AND

methodsA total of 590 cases of pGGN confirmed by pathology as lung adenocarcinoma or glandular prodromal lesions were collected retrospectively, of which 462 cases of pGGN were used as training and testing set, and 128 cases of pGGN as external verification set. The research is based on the Swin Transformer network and uses a five-fold cross-validation method to train the model. The diagnostic efficacy of deep learning model and radiologist on the external verification set was compared. The classification efficiency of the model is evaluated by confusion matrix, accuracy, precision and F1-score.

resultsThe accuracy of the training and testing sets of the deep learning model is 95.21% and 91.41% respectively, and the integration accuracy is 94.65%. The accuracy, precision and recall rate of the optimal model are 87.01%, 87.57% and 87.01% respectively, and the F1-score is 87.09%. In the external verification set, the accuracy of the model is 91.41%, and the F1-score is 91.42%. The classification efficiency of the deep learning model is better than that of radiologists.

conclusionThe multi-classification model based on deep learning has a good ability to predict the pathological subtypes of lung adenocarcinoma or glandular prodromal lesions with pGGN, and its classification efficiency is better than that of radiologists, which can improve the diagnostic accuracy of pulmonary pGGN. CRITICAL RELEVANCE STATEMENT: Swin Transformer deep learning models can noninvasively predict the pathological subtypes of pGGN, which can be used as a preoperative auxiliary diagnostic tool to improve the diagnostic accuracy of pGGN, thereby optimizing the prognosis of patients. KEY POINTS: The Swin Transformer model can predict the pathological subtype of pure ground-glass nodules. Compared with the performance of radiologists, the deep learning model performs better. Swin Transformer model can be used as a tool for preoperative diagnosis.

Indexed as

Deep learningGround-glass opacityLung adenocarcinomaPathological subtypesX-ray computed tomography

Identifiers

PMID41105350
PMCPMC12534675

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