Evidence map›Paper›PMID 41105332›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Analysis of clinical characteristics and prognostic factors in AIDS complicated by cryptococcal meningitis.

Yanlan Liang, Xiyang Dong, Yong Deng, Zhende Lin, Caixia Zheng, Jiaxuan Li, Yijie Lin, Huatang Zhang, Xing Wang, Wenwu Lin and 6 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yanlan Liang *Department of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Xiyang Dong *Department of Infection Diseases, Xiangya School of Medicine, Changde Hospital, Central South University (The First People's Hospital of Changde City), Changde, 415000, China.
Yong Deng *Department of Infection Diseases, The second People's Hospital of Pingxiang, Pingxiang, 337000, China.
Zhende Lin *Department of Infection Diseases, Anxi County Hospital, Quanzhou, 362000, China.
Caixia ZhengThe School of Clinical Medicine, Fujian Medical University, Fuzhou, 350122, China.
Jiaxuan LiThe School of Clinical Medicine, Fujian Medical University, Fuzhou, 350122, China.
Yijie LinDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Huatang ZhangDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Xing WangDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Wenwu LinDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Wencong HongDepartment of Respiratory and Critical Care Medicine, Nan'an Hospital, Quanzhou, 362000, China.
Su ZhangDepartment of Emergency Internal Medicine, Yuxi People's Hospital, Yuxi, 653100, China. 398042537@qq.com.
Zhijun SuDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. su2366@sina.com.
Weidong ZhaoDepartment of Laboratory Medicine, Clinical Medicine College, Dali University, Dali, 671000, China. wdzhao@dali.edu.cn.
Xiulan XueThe School of Clinical Medicine, Fujian Medical University, Fuzhou, 350122, China. xuexiulan2003@126.com.
Xue-Ping YuDepartment of Infection Diseases, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. xpyu15@fudan.edu.cn.

Funding

Major Science and Technology Innovation Project of Fujian Province 2023Y9269the National Natural Science Foundation of China 82370604the Natural Science Foundation of Fujian Province 2023J01239
6 · The paper itself

Abstract

objectiveTo analyze clinical features and identify prognostic factors in HIV/AIDS patients with cryptococcal meningitis (CM), and to develop a predictive model for short-term mortality.

methodsA multicenter retrospective study was conducted on 197 HIV/AIDS patients diagnosed with CM from 2013 to 2023. Clinical data were collected, and multivariate logistic regression was used to construct a prognostic model.

resultsThe median age was 48 years (IQR: 33-57.5), with 75.6% males. Common symptoms included headache (68.5%), fever (52.8%), and nausea/vomiting (49.2%). Independent risk factors for mortality were consciousness disturbance (OR = 7.785, P = 0.013) and elevated intracranial pressure (OR = 1.011, P = 0.023), while CD8

conclusionConsciousness disturbance, intracranial pressure, CD8

Indexed as

Acquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsMeningitis, CryptococcalAdultCD8-Positive T-LymphocytesFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsAIDSClinical characteristicsCryptococcal meningitisPredictive modelPrognostic risk factors

Identifiers

PMID41105332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.