Evidence map›Paper›PMID 41105324›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Investigation of risk factors and predictive model development for the progression of incarcerated inguinal hernia to strangulation.

Ning Chen, Mengjie Lv, Ying Chen, Dan Yao, Wei Yin, Juan Liu, Xiaoyu Zhang, Xiao Qiao, Haijian Zhao

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ning ChenDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.ORCID http://orcid.org/0000-0002-0226-6385
Mengjie LvDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.ORCID http://orcid.org/0009-0000-5877-9406
Ying ChenHongze District Huangji Street Community Health Service Center, Huaian, 223001, China.ORCID http://orcid.org/0009-0002-8267-1424
Dan YaoDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.
Wei YinDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.
Juan LiuDepartment of Economic Accounting, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.
Xiaoyu ZhangDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.
Xiao QiaoDepartment of Gastroenterology, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China.
Haijian ZhaoDepartment of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University (The Second People's Hospital of Huai'an), Huai'an, 223001, China. zhj_cn90@163.com.ORCID http://orcid.org/0000-0001-8436-1089

Funding

Jiangsu Commission of Health LKM2024047
6 · The paper itself

Abstract

purposeInguinal incarcerated hernia is a common disease in hernia surgery. This study was conducted to collect risk factors for strangulated inguinal hernia and to construct a predictive model to assist surgeons in decision-making.

methodsWe conducted a retrospective analysis of the clinical data from patients diagnosed with incarcerated inguinal hernias in the Department of Gastrointestinal Surgery, Huai'an Hospital Affiliated to Xuzhou Medical University, from January 2020 to January 2023. The independent risk factors for the progression of incarcerated inguinal hernias to strangulation were screened in the modeling group using univariate and logistic regression analyses and were used for construction of the nomogram prediction model.

resultsTenderness in the inguinal region (OR = 9.164, 95% CI = 2.540 ~ 33.066), intestinal obstruction (OR = 6.781, 95% CI = 1.568 ~ 29.330), elevated CRP (OR = 1.023, 95% CI = 1.009 ~ 1.037), and elevated neutrophils (OR = 1.253, 95% CI = 1.073 ~ 1.463) were identified as independent risk factors for the progression of incarcerated inguinal hernias to strangulation, while elevated prealbumin (OR = 0.992, 95% CI = 0.986 ~ 0.998) was identified as an independent protective factor. A risk prediction model for the progression of incarcerated inguinal hernias to strangulation was constructed based on these five observational indicators. The model's discrimination was tested by the ROC curve and showed AUC = 0.906, 95% CI = 0.851 ~ 0.962, and P < 0.05. The calibration curve showed good agreement with the ideal curve. The clinical decision curves showed that the model had good clinical utility.

conclusionTenderness in the inguinal region, combined intestinal obstruction, elevated CRP, and elevated neutrophils are independent risk factors for strangulation in incarcerated inguinal hernias, while elevated prealbumin is an independent protective factor. The constructed nomogram prediction model exhibits high sensitivity, specificity, and clinical utility.

Indexed as

Hernia, InguinalIntestinal ObstructionAdultAgedDisease ProgressionFemaleHumansMaleMiddle AgedNeutrophilsNomogramsRetrospective StudiesRisk FactorsIncarcerated herniaIntestinal necrosisNomogram modelRisk factors

Identifiers

PMID41105324
PMCPMC12534351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.