Evidence map›Paper›PMID 41105299›Full record

ArticleClinical & experimental metastasis2025

Postoperative stereotactic radiotherapy for brain metastases: results from a single-center retrospective analysis.

E K M Lam, D K C Leung, V H F Lee, B B T Taw, L F Li, G Ho, H C W Choi, B M F Cheung, J S C Cheung, Y P Ng and 2 more

Abstract read
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In one paragraph

Article in Clinical & experimental metastasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

E K M LamDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China. lkm496@ha.org.hk.
D K C LeungDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
V H F LeeDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
B B T TawDepartment of Neurosurgery, Queen Mary Hospital, Hong Kong SAR, China.
L F LiDepartment of Neurosurgery, Queen Mary Hospital, Hong Kong SAR, China.
G HoDepartment of Radiology, Queen Mary Hospital, Hong Kong SAR, China.
H C W ChoiSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
B M F CheungDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
J S C CheungDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
Y P NgDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
M Y LukDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
K K YuenDepartment of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate outcomes and prognostic factors in patients with resected brain metastases treated with postoperative SRS/SRT, and to develop a novel overall survival (OS) prognostic model. We retrospectively analyzed 70 patients (72 lesions) treated with postoperative SRS/SRT from July 2017 to May 2024. Outcomes included in-field and out-field intracranial progression-free survival (PFS), OS, and incidence of radionecrosis. Prognostic factors were identified using Cox regression. Recursive Partitioning Analysis (RPA) was used to construct an OS model. Median follow-up was 15.1 months. In-field PFS was 96.2% and 90.2%; Out-field PFS was 69.3% and 64.4% at 1 and 2 years respectively. Prior cranial radiotherapy was associated with worse out-field PFS. OS rates were 67.5% at 1 year, 46.7% at 2 years. ECOG performance status, time from surgery to radiotherapy of ≤ 56 days and biologically effective dose using α/ß of 10 (BED

Indexed as

Brain NeoplasmsRadiosurgeryAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateBrain metastasesHypofractionated stereotactic radiotherapyPostoperativeRadiosurgery

Identifiers

PMID41105299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.