Evidence map›Paper›PMID 41105295›Full record

ArticleThe international journal of cardiovascular imaging2025

Assessing extensive coronary artery disease using a myocardial jeopardy score based on coronary CT: long-term prognostic value.

Andreas A Giannopoulos, Alexia Rossi, Dimitrios V Moysidis, Jan A Schaab, Stjepan Jurisic, Tobia Albertini, Alessandro Candreva, Barbara E Stähli, Dominik C Benz, Ronny R Buechel and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andreas A GiannopoulosDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland. andreas.giannopoulos@usz.ch.
Alexia RossiDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Dimitrios V MoysidisDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Jan A SchaabDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Stjepan JurisicDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Tobia AlbertiniDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Alessandro CandrevaDepartment of Cardiology, University Heart Center, University Hospital Zurich, Zurich, CH-8091, Switzerland.
Barbara E StähliDepartment of Cardiology, University Heart Center, University Hospital Zurich, Zurich, CH-8091, Switzerland.
Dominik C BenzDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Ronny R BuechelDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Philipp A KaufmannDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.
Aju P PazhenkottilDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Raemistrasse 100, Zurich, CH-8091, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The British Cardiovascular Intervention Society Jeopardy Score (BCIS-JS) is an established, simplified scoring system for assessing coronary artery disease (CAD) extensiveness with excellent agreement between the invasive and the computed tomography (CT) angiography-based scores. Originally developed for use during invasive coronary angiography, it supports procedural planning and risk stratification by estimating the extent of myocardium at risk. The computed tomography (CT)-based version (CT-BCIS-JS) has shown excellent agreement with the invasive score. We aimed to investigate the value of the CT-BCIS-JS in predicting long-term outcomes. This retrospective single-center study included 337 patients referred for coronary CT angiography (CCTA). CT-BCIS-JS was calculated using a purpose-developed online calculator, and patients were divided into extensive and non-extensive CAD (BCIS ≥ 6 and BCIS < 6, respectively). The primary outcome was the composite of all-cause death and nonfatal myocardial infarction (MI) and the secondary outcome was major adverse cardiovascular events (MACEs), including all-cause mortality, MI, unstable angina requiring hospitalization, and coronary revascularization. Kaplan-Meier curves and multivariable-Cox regression analyses were utilized to compare outcomes between groups. Of the 337 patients, 249 (73.9%) patients had BCIS-JS < 6 and 88 (26.1%) patients had BCIS-JS ≥ 6. Overall, the primary outcome occurred in 47 (13.9%) patients over a median follow-up of 6.8 years (interquartile range 5.7-8.5 years). Thirthy-eight of them (43.2%) had BCIS-JS ≥ 6 compared to 9 (3.6%) in the BCIS-JS < 6 group (adjusted hazard ratio [aHR]: 11.15; 95% CI 4.97-24.99; p < 0.001). The secondary outcome occurred in 77 patients (87.5%) who had BCIS-JS ≥ 6 compared to 20 (8.0%) in the BCIS-JS < 6 group (aHR: 19.92; 95% CI: 11.40-34.81; p < 0.001). CT-BCIS-JS allows excellent risk stratification in patients with known or suspected CAD. Anatomically extensive CAD identified with the CT-BCIS-JS is a strong predictor of higher mortality, nonfatal MI, and MACE. Graphical representation of the definition, calculation and classification as well as the long-term prognostic significance of the coronary CT Angiography-Based British Cardiovascular Intervention Society Jeopardy Score (CT-BCIS-JS). The figure illustrates the method used to quantify myocardial jeopardy, the scoring algorithm, and its application in risk stratification for extensive coronary artery disease (CAD). Kaplan-Meier survival curves demonstrate the long-term clinical impact of the CT-BCIS-JS, with higher scores associated with poorer event-free survival.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDecision Support TechniquesMultidetector Computed TomographyAgedFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPredictive Value of TestsPrognosisBritish cardiovascular intervention society jeopardy scoreClinical outcomesCoronary artery diseaseCoronary computed tomography angiographyMajor adverse cardiovascular eventsPrognostic significance

Identifiers

PMID41105295
PMCPMC12628459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.