Evidence map›Paper›PMID 41105020›Full record

ArticlePerfusion2026

Neuromonitoring and neuroprotection during neonatal aortic arch surgery: A United Kingdom and Ireland survey.

William M McDevitt, Indie Bilkhoo, Edmund Carver, Timothy J Jones, Stefano Seri, Barney R Scholefield, Nigel E Drury

Abstract read
In one paragraph

Article in Perfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

William M McDevittNeurophysiology, Birmingham Children's Hospital, Birmingham, UK.ORCID 0000-0003-1547-5052
Indie BilkhooClinical Perfusion, Birmingham Children's Hospital, Birmingham, UK.
Edmund CarverPaediatric Anaesthesia, Birmingham Children's Hospital, Birmingham, UK.
Timothy J JonesCardiovascular Sciences, University of Birmingham, Birmingham, UK.
Stefano SeriNeurophysiology, Birmingham Children's Hospital, Birmingham, UK.
Barney R ScholefieldCritical Care Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Nigel E DruryCardiovascular Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0001-9012-6683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionNeonatal aortic arch surgery is associated with neurological morbidity of varying severity which is detected and potentially limited through neuroprotective strategies. We conducted a survey of healthcare professionals at all neonatal cardiac surgery centres in the United Kingdom and Ireland to determine current intraoperative neuromonitoring and neuroprotection practice.MethodsAn online cross-sectional survey was sent to congenital cardiac surgeons, cardiac anaesthetists, clinical perfusion scientists, and clinical neurophysiology professionals in all 12 level 1 paediatric cardiac surgical centres. Information was sought on their current clinical practice in neonates undergoing aortic arch surgery, including pharmacological management, cardiopulmonary bypass, acid-base and blood pressure management, neuromonitoring, and hypothermic circulatory arrest, and the feasibility and willingness to participate in a future clinical trial of neuroprotective strategies in these patients.ResultsWe received 55 (34%) responses, including representatives of all four clinical disciplines in 9 (75%) centres. Cooling to a nasopharyngeal temperature of 18°C before hypothermic circulatory arrest, selective antegrade cerebral perfusion, and near-infrared spectroscopy (NIRS) monitoring are common practice, whereas pharmacology, acid-base management, blood pressure and flow parameters, and NIRS-based interventions vary. In 7 (58%) centres, respondents from all four disciplines were willing to consider participation in a future clinical trial on neuroprotection.ConclusionsAspects of intraoperative neuroprotection and neuromonitoring are common across centres, although key areas of practice differ between practitioners and institutions. Most respondents were willing to participate in a future multi-centre clinical trial, which suggests clinical equipoise in the optimal strategy to protect the neonatal brain during aortic arch surgery.

Indexed as

Aorta, ThoracicMonitoring, IntraoperativeNeuroprotectionCross-Sectional StudiesFemaleHumansInfant, NewbornIrelandSurveys and QuestionnairesUnited Kingdomcardiac surgerycongenital heart diseaseelectroencephalographynear-infrared spectroscopyneuromonitoringneuroprotection

Identifiers

PMID41105020
PMCPMC13490662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.