Evidence map›Paper›PMID 41104944›Full record

ArticleJournal of bacteriology2025

The PA2803-encoded PcrP exhibits a novel non-catalytic function and contributes to polymyxin B resistance in

T Salpadoru, S Khanam, V A Borin, Ma A Achour, Denise Oh, M Kanik, P C Gallage, A Khanov, M Hull, S P Pitre and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Host-derived stimuli alter intracellular calcium levels inApplied and environmental microbiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

T SalpadoruDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.ORCID 0000-0002-3711-5501
S KhanamDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
V A BorinDepartment of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma, USA.
Ma A AchourDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Denise OhDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, USA.
M KanikDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, USA.
P C GallageDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma, USA.
A KhanovDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
M HullDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
S P PitreDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma, USA.
P K AgarwalDepartment of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma, USA.
M J FranklinDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana, USA.
M A PatrauchanDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.ORCID 0000-0002-0495-3867

Funding

ZFC3H1 Regulation of Host Defense and Influenza A Virus PathogenesisP20GM103648 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHENG, YONG · 2013 to 2022
$22.3M
Calcium signaling controls Pseudomonas aeruginosa invasion and adaptation to the host intracellular environmentR15GM124670 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI PATRAUCHAN, MARIANNA M. A. · 2017 to 2023
$1.1M
Biophysical Model of Enzyme Catalysis: Conformational sub-states, solvent coupling and energy networksR01GM148886 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI David Wayne Ussery · 2023 to 2026
$888k
Role of Ribosome Hibernation in the Tolerance of P. aeruginosa Biofilms to AntibioticsR21AI154171 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI FRANKLIN, MICHAEL J. · 2021 to 2022
$396k
National Science Foundation OAC-1531128, OAC-2216084NIAID NIH HHS R21 AI154171NIGMS NIH HHS P20 GM103648NIGMS NIH HHS R01 GM148886NIGMS NIH HHS R15 GM124670NIH HHS 1R15GM124670-0, P20GM103648NIH HHS AI154171NIH HHS GM148886
6 · The paper itself

Abstract

The opportunistic human pathogen

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialPolymyxin BPseudomonas aeruginosaCalciumGene Expression Regulation, BacterialAnti-Bacterial AgentsBacterial ProteinsCalciumPolymyxin BACP3cystic fibrosisevolutionary divergenceHAD-superfamilynon-catalyticPA3518polymyxin-B resistance

Identifiers

PMID41104944
PMCPMC12632274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.