Coping with the Blues: Simple and Photo-Stable Dye for Long-Term Live-Cell Imaging.

Justine V Schwarte, Christophe Lamy, Salves Cornelis, Ora Hazak, Katharina M Fromm

Abstract read

In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justine V SchwarteDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, Fribourg, 1700, Switzerland.ORCID 0000-0003-4608-2526

Christophe LamyDepartment of Biology, University of Fribourg, Chemin du Musée 5, Fribourg, 1700, Switzerland.ORCID 0000-0001-6944-9787

Salves CornelisDepartment of Biology, University of Fribourg, Chemin du Musée 5, Fribourg, 1700, Switzerland.ORCID 0000-0002-3391-0946

Ora HazakDepartment of Biology, University of Fribourg, Chemin du Musée 5, Fribourg, 1700, Switzerland.ORCID 0000-0002-9182-3330

Katharina M FrommDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, Fribourg, 1700, Switzerland.ORCID 0000-0002-1168-0123

Funding

Faculté des Sciences et de Médecine, Université de FribourgFribourg Center for Nanomaterials (FriMat)National Center of Competence in Research Bio-Inspired Materials, University of FribourgSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 178827

6 · The paper itself

Abstract

Dyes for long-term imaging of live cells are rare, especially in the blue region, as they need to be nontoxic and photo-stable. New simple pyrene-derived dyes have been synthesized and fully characterized, showing good cellular uptake, intense emission, and excellent stability. Their unusual stability secret lies in their flexible conformation, evidenced by the solid-state structures of coordination compounds obtained from the dyes and by

Indexed as

Coloring AgentsFluorescent DyesPyrenesHeLa CellsHumansColoring AgentsFluorescent DyespyrenePyrenesfluorescent probesimaging agentslight induced configuration changephotobleaching stabilityphotochemistry

Identifiers

PMID41104920

DOI10.1002/chem.202501360

PMCPMC12712751

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.