Evidence map›Paper›PMID 41104868›Full record

ReviewMolecular medicine reports2026

Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of  cardiovascular diseases (Review).

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu

Abstract readReview
In one paragraph

Review in Molecular medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yishuo ZhangCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Shanshan ZhangCollege of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Changchun, Jilin 130117, P.R. China.
Yijing LiCollege of Basic Medical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130017, P.R. China.
Wenqi JinResearch Center of Traditional Chinese Medicine, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin 130021, P.R. China.
Liya ZhouCollege of Basic Medical Sciences, Changchun University of Chinese Medicine, Changchun, Jilin 130017, P.R. China.
Jing LuResearch Center of Traditional Chinese Medicine, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin 130021, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are among the main factors impacting negatively human health on a global scale. Every year, there is an increase in the prevalence of CVDs despite advancements in therapy for managing traditional risk factors. Research on exosomes is has garnered great interest due to their role in regulating intercellular communication. Exosome‑mediated epigenetic regulation is involved in the interaction between circulating cells and blood arteries, as well as in intercellular communication processes, and exosomes serve as biomarkers of cell activation. The present study aimed to summarize the recent research on exosome‑mediated epigenetic regulation mechanisms, as well as the roles of exosomes in the pathology and diagnosis of CVDs, which may increase the current understanding of the precise functions that exosomes play in the development of CVDs.

Indexed as

Cardiovascular DiseasesEpigenesis, GeneticExosomesAnimalsBiomarkersCell CommunicationHumansBiomarkerscardiovascular diseasesdiagnosis and treatmentepigenetic regulationexosomesmechanism

Identifiers

PMID41104868
PMCPMC12555894

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.