Evidence map›Paper›PMID 41104687›Full record

ArticleGut microbes2025

Yunhuan Gao, Yi Shi, Ningning Zhu, Yang Hao, Juanjuan Wang, Yuan Zhang, Rongcun Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Tissue adaptation of eosinophils.Journal of leukocyte biology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yunhuan GaoDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Yi ShiSchool of Statistics and Data Science, Shanghai University of International Business and Economics, Shanghai, China.
Ningning ZhuDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Yang HaoDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Juanjuan WangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Yuan ZhangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Rongcun YangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.ORCID 0000-0002-5826-4493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut homeostasis is critical for systemic health, and its disruption is implicated in various diseases, including metabolic disorders. Gut-resident macrophages play a pivotal role in maintaining intestinal homeostasis, yet the mechanisms underlying their differentiation and function remain incompletely understood. Using single-cell RNA sequencing (scRNA-seq), we found a key regulatory axis in which gut microbiota-derived butyrate induces the differentiation of Nr4a1

Indexed as

ButyratesCore Binding Factor Alpha 3 SubunitGastrointestinal MicrobiomeMacrophagesNuclear Receptor Subfamily 4, Group A, Member 1AnimalsCell DifferentiationColitisHomeostasisHumansMaleMAP Kinase Signaling SystemMiceMice, Inbred C57BLRNA, Long NoncodingTristetraprolinButyratesCore Binding Factor Alpha 3 SubunitNr4a1 protein, mouseNuclear Receptor Subfamily 4, Group A, Member 1RNA, Long NoncodingRunx3 protein, mouseTristetraprolinGut microbeNr4a1resident macrophageRUNX3ZFP36

Identifiers

PMID41104687
PMCPMC12536639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.