ArticleMovement disorders clinical practice2026
Investigating Sleep Concerns in Cervical Dystonia.
Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHeterogenous, small cohorts, and co-occurrence of pain and psychiatric burden complicate understanding of sleep in dystonia.
objectiveTo investigate sleep concerns in cervical dystonia (CD).
methodsLongitudinal data from CD-PROBE on subjects who were toxin-naïve, new to practice, or without injections for at least 16 weeks were analyzed. Cervical Dystonia Impact Profile captured sleep disturbances. Impact of OnabotulinumtoxinA on sleep was assessed using multilevel mixed models, controlling for demographics, dystonia severity, mood, and pain.
results56% (n = 1037) reported concerns with sleep initiation, restfulness, maintenance, and total time. Initial injection led to a clear improvement in sleep. (P < 0.001) Motor severity (β: 0.20, P < 0.001), mood (β: 0.36, P < 0.001), and pain (β: 0.58, P < 0.001) predicted sleep improvement (n = 502) over three OnabotulinumtoxinA cycles.
conclusionsSleep concerns are common in CD, with initial and subsequent improvement with OnabotulinumtoxinA. Impact of mood and pain on sleep highlights the importance of non-motor features.
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