Evidence map›Paper›PMID 41104443›Full record

ArticleTransfusion2025

Babesia nucleic acid prevalence among blood donors in southern Québec.

Christian Renaud, Milena Fedorova, Nathalie C Simard, Jean-François Côté, Jeffrey M Linnen, Genevieve Baron, François Milord, Karine Thivierge, Alejandra Irace-Cima, Jamel A Groves and 6 more

Abstract read
In one paragraph

Article in Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christian RenaudMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.
Milena FedorovaMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.
Nathalie C SimardMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.ORCID https://orcid.org/0009-0009-7262-9530
Jean-François CôtéMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.
Jeffrey M LinnenGrifols Diagnostic Solutions, San Diego, California, USA.
Genevieve BaronDirection de santé publique, CIUSSS de l'Estrie-CHUS, Sherbrooke, Québec, Canada.
François MilordDirection de santé publique, CISSS de la Montérégie-centre, Greenfield Park, Québec, Canada.
Karine ThiviergeLaboratoire de santé publique du Québec, Institut national de santé publique du Québec, Sainte-Anne-de-Bellevue, Québec, Canada.
Alejandra Irace-CimaDirection des risques biologiques, Institut national de santé publique du Québec, Montréal, Québec, Canada.
Jamel A GrovesScientific Affairs, American Red Cross, Rockville, Maryland, USA.ORCID https://orcid.org/0009-0007-9334-3158
Rebecca L TownsendScientific Affairs, American Red Cross, Rockville, Maryland, USA.
Paula SaaScientific Affairs, American Red Cross, Rockville, Maryland, USA.ORCID https://orcid.org/0000-0001-6077-4532
Laura TonnettiScientific Affairs, American Red Cross, Rockville, Maryland, USA.ORCID https://orcid.org/0000-0001-7735-8420
Susan L StramerInfectious Diseases Consultant, North Potomac, Maryland, USA.
Marc GermainMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.
Antoine LewinMedical Affairs and Innovation, Héma-Québec, Montréal, Québec, Canada.ORCID https://orcid.org/0000-0003-1748-4198

Funding

Héma-Québec
6 · The paper itself

Abstract

backgroundTick-borne diseases are on the rise in Canada, and southern Québec is considered one of the highest-risk regions for Babesia emergence. Babesia is easily transmissible through blood transfusion and was the most common transfusion-transmitted infection in the United States before the implementation of nucleic acid testing (NAT) in 2020. Babesia NAT is not yet implemented in Canada, and prevalence studies are necessary for risk assessment. Therefore, Héma-Québec performed a new prevalence study in the summer of 2024. STUDY DESIGN AND

methodsWhole blood and platelet donors were sampled between June 1, 2024, and October 31, 2024, in four high-risk administrative regions in southern Québec (i.e., Estrie, Montérégie, Montréal, and Mauricie-Centre-du-Québec). The samples were tested at the American Red Cross with a qualitative Babesia NAT, i.e., the Procleix Babesia assay.

resultsA total of 28,800 donations were collected and tested from four high-risk administrative regions of the province of Quebec. All donations tested negative for Babesia NAT. DISCUSSION: While public health data indicate that Babesia microti is emerging in southern Québec, to date, the risk of acquiring babesiosis through transfusion of blood products remains low. Partnership with public health authorities and clinicians remains essential to keep abreast of the emergence of such cases.

Indexed as

BabesiaBabesiosisBlood DonorsDNA, ProtozoanAdultFemaleHumansMaleMiddle AgedPrevalenceQuebecDNA, Protozoanemerging pathogensinfectious disease transmissionrisk factors

Identifiers

PMID41104443
PMCPMC12531930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.