Evidence map›Paper›PMID 41104326›Full record

ArticleSleep advances : a journal of the Sleep Research Society2025

Laura Dovek, Carolyn E Tinsley, Katelyn Gutowsky, Kayla L McDaniel, Nathan M McGuire, Lorenzo R Nungaray, Zoe Potter, Matthias Ruffins, Noah E P Milman, Claire Wong and 3 more

Abstract read
In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

13 authors.

Laura DovekDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
Carolyn E TinsleyDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
Katelyn GutowskyPortland VA Research Foundation, Portland, OR, United States.
Kayla L McDanielPortland VA Research Foundation, Portland, OR, United States.
Nathan M McGuirePortland VA Research Foundation, Portland, OR, United States.
Lorenzo R NungarayPortland VA Research Foundation, Portland, OR, United States.
Zoe PotterPortland VA Research Foundation, Portland, OR, United States.
Matthias RuffinsPortland VA Research Foundation, Portland, OR, United States.
Noah E P MilmanDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
Claire WongPortland VA Research Foundation, Portland, OR, United States.
Amala SoumyanathDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
Nora E GrayDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
Miranda M LimDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.ORCID https://orcid.org/0000-0003-3876-3196

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2020 to 2024
$6.1M
Neuroscience of Aging, Neurodegeneration and Alzheimer’s DiseaseT32AG055378 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI JACOB RABER, HENRYK F URBANSKI · 2018 to 2026
$4.3M
BLRD VA I01 BX006155BLRD VA IK2 BX002712NCCIH NIH HHS T32 AT002688NCCIH NIH HHS U19 AT010829NIA NIH HHS P30 AG066518NIA NIH HHS T32 AG055378
6 · The paper itself

Abstract

Age-related sleep disruption is common in older adults. Not only does the total amount of time spent in sleep decline, but also the number of arousals during sleep increases with age. As sleep is important for both memory consolidation and to prevent neurodegenerative pathology, this decline in sleep and/or sleep consolidation may underlie age-related cognitive decline and dementias. Furthermore, treatment of sleep disruption can improve quality of life. However, few interventions have successfully reversed age-related sleep decline. Extracts from the plant

Indexed as

aginganimal modelsNREM–REM cyclesREM sleepsleep and the brain

Identifiers

PMID41104326
PMCPMC12527346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.