ArticleVirus evolution2025
Phylogeographic evaluation of the effectiveness of Canadian travel restrictions in reducing SARS-CoV-2 variant importations and burden.
Article in Virus evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluating travel restriction effectiveness in mitigating infectious disease burden, exemplified by COVID-19, is critical for informing pandemic response policy, yet methodologies and results evaluating their effectiveness vary considerably. We hypothesized Canadian COVID-19 travel restrictions, including flight bans and enhanced screening, targeting focal source countries where SARS-CoV-2 variants of concern (VOCs) Alpha, Beta, Gamma, Delta, and Omicron were first identified, were variably effective towards averting introductions and case burden. We conducted a retrospective observational study using all the publicly available SARS-CoV-2 sequences and COVID-19 diagnoses up to March 2022, after which polymerase chain reaction (PCR) testing and surveillance sequencing decreased. Average daily variant cases were estimated across global regions and Canadian provinces, which informed subsampling probabilities for sequences for up to 50 000 sequences for VOCs and variants of interest from late 2020 to early 2022. Maximum likelihood phylogeographic methods were used to infer Canadian SARS-CoV-2 sublineages and singletons, representing international viral introductions with and without domestically sampled descendants. Reduction of sublineage and singleton introduction rates and proportional contributions from focal sources were quantified following interventions' introductions. Sublineages and cases averted
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