Evidence map›Paper›PMID 41104022›Full record

ArticlePulmonary circulation2025

Late Onset Pulmonary Arterial Hypertension Associated With Features of Pulmonary Veno-Occlusive Disease and Rare Heterozygous Variants of

Vasile Foris, Luka Brcic, Peter Dorfmüller, Christina A Eichstaedt, Ekkehard Grünig, Philipp Douschan, Teresa John, Katarina Zeder, Michael Fuchsjäger, Nikolaus Kneidinger and 2 more

Abstract read
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vasile ForisDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.ORCID https://orcid.org/0000-0002-8863-0298
Luka BrcicDepartment of Pathology Medical University of Vienna Austria.
Peter DorfmüllerInstitute for Lung Health (ILH), German Centre for Lung Research (DZL) Germany.
Christina A EichstaedtCenter for Pulmonary Hypertension Thoraxklinik-Heidelberg GmbH at Heidelberg University Hospital and Translational Lung Research Center (TLRC), German Center for Lung Research (DZL) Heidelberg Germany.
Ekkehard GrünigCenter for Pulmonary Hypertension Thoraxklinik-Heidelberg GmbH at Heidelberg University Hospital and Translational Lung Research Center (TLRC), German Center for Lung Research (DZL) Heidelberg Germany.
Philipp DouschanDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.ORCID https://orcid.org/0000-0003-2505-7831
Teresa JohnDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.
Katarina ZederDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.ORCID https://orcid.org/0000-0002-8415-727X
Michael FuchsjägerDivision of General Radiology, Department of Radiology Medical University of Graz Graz Austria.
Nikolaus KneidingerDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.
Gabor KovacsDepartment of Internal Medicine, Division of Respiratory Medicine, Lung Research Cluster Medical University of Graz Graz Austria.
Horst OlschewskiFaculty of Medicine Sigmund Freud Private University Vienna Vienna Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural history of late-onset pulmonary arterial hypertension (PAH) with features of venous/capillary involvement and the associations with rare variants in PAH genes are not well known. We report a case of a female patient who developed severe PAH at the age of 70. Two years before, lung histology was obtained showing features of pulmonary veno-occlusive disease. Genetic testing revealed that the patient was harbouring two rare genetic variants in the

Indexed as

case reporthistologynon‐plexiform lesionspulmonary hypertensionpulmonary vasodilator therapy

Identifiers

PMID41104022
PMCPMC12521608

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.