ArticleCureus2025
Corneal Endothelial Cell Damage Following Bee Stings: A Report of Two Cases.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Corneal bee stings cause inflammation through direct venom toxicity and type I hypersensitivity reactions that can lead to endothelial cell damage. In severe cases, these injuries can progress to bullous keratopathy, a condition that necessitates corneal transplantation. Here, we reported two cases in which transparent healing was achieved through steroid treatment, yet subsequent corneal endothelial cell damage ensued. In the initial case, an 81-year-old male sustained a sting in the left eye from a honeybee. Initial visual acuity was 20/17 in the right eye and 20/33 in the left eye. A preliminary evaluation of the patient's eye revealed the presence of corneal epithelial damage, Descemet's membrane folds, and corneal edema measuring approximately 2 mm in the inferonasal peripheral cornea. Following treatment with topical steroids and oral betamethasone from day one, the cornea exhibited a transparent healing response with visual acuity improving to 20/33 in the affected eye. However, a significant decrease in endothelial cell density was observed, measuring at 1,306 cells/mm² in the affected eye, compared to the normal density of 2,677 cells/mm² in the contralateral eye. In the second case, a 49-year-old male with a history of laser-assisted in situ keratomileusis surgery was stung in the right eye by a paper wasp (
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