Evidence map›Paper›PMID 41103803›Full record

ArticleExposome2021

Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction.

Karthik Suresh Arulalan, Javier Huayta, Jonathan W Stallrich, Adriana San-Miguel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exposome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karthik Suresh ArulalanDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA.
Javier HuaytaDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0001-9857-6080
Jonathan W StallrichDepartment of Statistics, North Carolina State University, Raleigh, NC, USA.
Adriana San-MiguelDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0003-0172-2163

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Elucidating Synaptic Regulators via High-Throughput Morphology CharacterizationR00AG046911 · NIA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAN MIGUEL, ADRIANA · 2016 to 2018
$984k
A platform for in vivo lifelong tracking of aging genes and lifespan prediction under precise environments in C. elegans.R21AG059099 · NIA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI FLORES, KEVIN, SAN MIGUEL, ADRIANA · 2019 to 2020
$401k
NIA NIH HHS R00 AG046911NIA NIH HHS R21 AG059099NIH HHS P40 OD010440
6 · The paper itself

Abstract

Chemical agents released into the environment can induce oxidative stress in organisms, which is detrimental for health. Although environmental exposures typically include multiple chemicals, organismal studies on oxidative stress derived from chemical agents commonly study exposures to individual compounds. In this work, we explore how chemical mixtures drive the oxidative stress response under various conditions in the nematode

Indexed as

Caenorhabditis eleganscomplex exposuremodel organismoxidative stresssimplex centroid designxenobiotics

Identifiers

PMID41103803
PMCPMC12525721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.