Evidence map›Paper›PMID 41103794›Full record

ArticleIntegrative medicine (Encinitas, Calif.)2025

Treatment of Schizophrenia and Depression Caused by Environmental Toxins and Dysbiosis: A Functional Medicine Case Study.

Vanessa Gourdine

Abstract readCase Reports
In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Vanessa GourdineThe Functional Medicine Centers for Personalized Care, LLC; Paramus, New Jersey, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of mental health disorders increased by about 40% from 2019 to 2023. The incidence of mental health disorders continues to escalate while the outcomes remain poor. The outcomes of psychopharmacology are mildly to moderately effective and rarely, if ever, result in a cure. The expectation is a lifetime use of medication for symptomatic management. The following case is an example of an integrative mind-body approach that may lead to an actual cure of psychiatric conditions when focused on neuroinflammation and not solely on neurotransmitters. The current case involves a young man who had been hospitalized seven times within seven years and treated with multiple attempts at various combinations of polypharmacy, resulting in similar outcomes and more hospitalizations. He sought a functional medicine approach due to the poor outcomes with conventional treatment. Subsequently, he was admitted to our outpatient facility utilizing a multi-systems model of an in-depth mind-body assessment. The treatment was based on inflammatory markers likely triggered by multiple toxin exposures, aimed at eliminating the sources of inflammation and introducing lifestyle and diet modifications to support detoxification. The outcomes obtained were extraordinary, with a total remission of all symptoms up to and including a post-treatment two-year follow-up assessment. This suggests that our approach to creating health outcomes needs to be personalized and integrative of both mind and body to achieve the best outcomes. The case presents an alternative approach to conventional treatment involving polypharmacy and psychiatric hospitalizations.

Identifiers

PMID41103794
PMCPMC12520242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.