Evidence map›Paper›PMID 41103710›Full record

ArticleFrontiers in medicine2025

Case Report: Clinical metastasis characteristics of lung adenosquamous carcinoma with

Xi Chen, Kewei Ma, Xiaobo Ma, Wenhao Zhu, Bo Liu, Xiumei Duan, Yinghui Xu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xi ChenCancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Kewei MaCancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Xiaobo MaDepartment of Pathology, The First Hospital of Jilin University, Changchun, Jilin, China.
Wenhao ZhuCancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Bo LiuCancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Xiumei DuanDepartment of Pathology, The First Hospital of Jilin University, Changchun, Jilin, China.
Yinghui XuCancer Center, The First Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosquamous carcinoma (ASC) of the lung is a rare and aggressive subtype of non-small-cell lung cancer, with a poor prognosis. Previous studies have revealed the existence of numerous oncogenic mutations shared between the adeno and squamous components, thereby implying a potential link between these two pathologies. Nevertheless, the genetic origin and underlying mechanisms of such a connection remain subjects of controversy. Here, we present a remarkable case of ASC where the primary tumor and mediastinal lymph node (LN) metastasis were adenosquamous, while the hilar LN metastasis was pure squamous cell carcinoma. Remarkably, a

Indexed as

adeno-to-squamous transdifferentiationlung adenosquamous carcinomamonoclonal originROS1tumor immune microenvironment

Identifiers

PMID41103710
PMCPMC12521446

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.