Evidence map›Paper›PMID 41103688›Full record

ReviewBiochemia medica2025

National recommendations of the Croatian society of medical biochemistry and laboratory medicine: Thyroid function tests from the laboratory point of view.

Adriana Bokulić, Ivana Zec, Domagoj Marijančević, Marija Siter Kuprešanin, Sanja Goreta, Anamarija Đuras, Koraljka Đurić, Sanda Jelisavac Ćosić, Iva Lukić, Tihana Serdar Hiršl and 4 more

Abstract readReview
In one paragraph

Review in Biochemia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adriana BokulićDepartment of Clinical Chemistry, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.
Ivana ZecDepartment of Clinical Chemistry, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.
Domagoj MarijančevićDepartment of Clinical Chemistry, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.
Marija Siter KuprešaninDepartment of Medical Laboratory Diagnostics, University Hospital Sveti Duh, Zagreb, Croatia.
Sanja GoretaDepartment of Clinical Chemistry, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.
Anamarija ĐurasDepartment of Medical Biochemistry Laboratory, General Hospital Varaždin, Varaždin, Croatia.
Koraljka ĐurićSchool of Medicine, Catholic University of Croatia, Zagreb, Croatia.
Sanda Jelisavac ĆosićDepartment of Nuclear Medicine and Radiation Protection, University Hospital Centre Zagreb, Croatia.
Iva LukićClinical Institute of Laboratory Diagnostics, University Hospital Centre Osijek, Osijek, Croatia.
Tihana Serdar HiršlSynlab Croatia, Polyclinic for Medical Laboratory Diagnostics, Zagreb, Croatia.
Lada StanišićDepartment of Medical Laboratory Diagnostics, University Hospital of Split, Split, Croatia.
Daniela Šupe-DomićDepartment of Medical Laboratory Diagnostics, University Hospital of Split, Split, Croatia.
Alenka PezoMedical Biochemistry Laboratory Alenka Pezo, Zagreb, Croatia.
Marija KocijančićInstitute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid function tests (TFTs) - thyroid stimulating hormone (TSH), total triiodothyronine (T3), total thyroxine (T4), free triiodothyronine (FT3), free thyroxine (FT4), thyroid peroxidase antibodies (anti-TPO), thyroglobulin antibodies (anti-Tg), TSH receptors antibodies (anti-TSHR), and thyroglobulin (Tg) - are used to diagnose thyroid disorders and are crucial biomarkers for monitoring and managing thyroid cancer. The 2022 national survey results revealed that thyroid function testing is not standardized among Croatian medical-biochemistry laboratories. Laboratories follow individual protocols at each testing stage, from patient preparation to result reporting. To address this, the Working group for laboratory endocrinology of the Croatian society of medical biochemistry and laboratory medicine has developed recommendations based on the latest national and international guidelines, research and the authors' expert opinion. The document aims to standardize all phases of thyroid function testing, with 7 preanalytical, 12 analytical, and 8 postanalytical recommendations, each supported by expert explanations. While primarily directed at Croatian laboratory professionals, this document is also relevant to other healthcare professionals managing thyroid-related health issues.

Indexed as

Thyroid DiseasesThyroid Function TestsAutoantibodiesCroatiaHumansSocieties, MedicalThyroid GlandAutoantibodiesrecommendationsstandardizationthyroid function tests

Identifiers

PMID41103688
PMCPMC12523660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.