Evidence map›Paper›PMID 41103603›Full record

ArticleClinical case reports2025

Immediate Bilateral Sequential Keratoplasty in a 13-Year-Old Boy With Perforated Corneal Ulcer Secondary to Exposure Keratopathy.

Javad Sadeghi, Mohammadreza Sedaghat, Mitra Karimi Amir Abadi, Mehrdad Motamed Shariati

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Javad SadeghiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.
Mohammadreza SedaghatEye Research Center Mashhad University of Medical Sciences Mashhad Iran.
Mitra Karimi Amir AbadiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0009-0001-3444-3868
Mehrdad Motamed ShariatiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-8680-5560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To present the challenging scenario of a 13-year-old patient in the ICU with bilateral corneal perforations secondary to EK, who underwent immediate sequential bilateral penetrating keratoplasty. Furthermore, we explore the treatment outcomes of this approach. A 13-year-old boy presented with decreased vision in both eyes. Upon ophthalmic examination, we identified bilateral perforated corneal ulcers with iris prolapse and a flat anterior chamber (AC). Due to the bilateral corneal perforations and the heightened risk of infectious endophthalmitis, immediate bilateral sequential penetrating keratoplasty (PKP) was carried out for the patient the day after presentation to our emergency room (ER). Over the 6-month follow-up period, no signs of graft rejection or infection were observed. This is the first reported case of immediate sequential bilateral PK. In emergent situations like bilateral corneal perforation, sequential bilateral surgery proves to be a reasonable and effective option.

Indexed as

corneacorneal transplantationexposure keratopathyintensive care unitspenetrating keratoplasty

Identifiers

PMID41103603
PMCPMC12521819

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.