ArticleFrontiers in neurology2025
Effects of manual carotid compression in endovascular thrombectomy for acute anterior circulation large-vessel occlusion: a multicenter, propensity score-matching study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Randomized controlled trials suggested that balloon guide catheters for proximal flow control (PFC) in endovascular thrombectomy (EVT) for acute anterior circulation large-vessel occlusion (LVO) have unsatisfactory results. Our study aimed to explore effects of manual carotid compression (MCC) achieving temporary PFC in EVT, without interfering with endovascular procedures. Methods: We retrospectively included 203 patients with acute occlusion of the intracranial internal carotid artery or the M1 or proximal M2 segments of the middle cerebral artery undergoing EVT from three independent centers ( Results: In the overall cohort, the median age was 71 years (IQR 62-76), with 119 male patients (58.6%). Baseline characteristics between the two groups differed significantly in terms of hypertension ( Conclusion: MCC in EVT for patients with acute anterior circulation LVO in our cohort could improve the 90-day mRS score and the proportion of patients with scores of 0-1, increase the reperfusion rate after the first pass and enhance early neurological improvement, while decreasing the incidence of ICH and sICH.
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