Evidence map›Paper›PMID 41103463›Full record

ArticleFrontiers in public health2025

Understanding vaccine hesitancy through the lens of trust and the 3C model: evidence from Chinese General Social Survey 2021.

Bo Dong, Hengxuan Xu, Yuantao Qi, Yifan Li

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Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Bo Dong *School of Public Health, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.
Hengxuan Xu *Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Yuantao QiShandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Yifan LiShandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Trust is critical in managing infectious disease outbreaks, influencing both healthcare delivery and public compliance. While existing studies suggest trust reduces vaccine hesitancy (VH), the mechanisms remain unclear, particularly how different types of trust impact VH. Methods: This study uses data from the 2021 Chinese General Social Survey (CGSS), analyzing responses from 7,907 individuals. VH was assessed via COVID-19 vaccination status. Four trust types-generalized, government, doctor, and internet trust-were examined using binary probit regression. Structural equation modeling analyzed the mediating role of psychological factors: self-confidence, complacency, and responsibility. Robustness checks employed alternative dependent variables and models. Results: Trust exerts a significant negative predictive effect on vaccine hesitancy, suggesting that higher levels reduce the likelihood of vaccine hesitancy. This finding remains statistically significant after robustness tests. However, trust in the government and physician exert a greater influence on vaccine hesitancy than generalized trust and online trust. The three psychological antecedents-confidence, complacency, and collective responsibility-serve a crucial mediating role between trust and vaccine hesitancy. Most vaccinations were community-organized, followed by voluntary and employer-organized vaccination. Higher VH correlated with lower trust across all types, though most hesitancy levels occurred among those with moderate to high trust. Conclusion: Strengthening trust-especially in government and healthcare providers-is essential to reducing VH. Psychological determinants like confidence, complacency, and responsibility play key roles in vaccination decisions. Tackling VH requires multi-level strategies: fostering public trust, enhancing government transparency, empowering healthcare professionals, combating online misinformation, and leveraging community initiatives.

Indexed as

COVID-19COVID-19 VaccinesTrustVaccinationVaccination HesitancyAdolescentAdultChinaEast Asian PeopleFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultCOVID-19 VaccinesChinaCOVID-19psychological antecedenttrustvaccine hesitancy

Identifiers

PMID41103463
PMCPMC12521134

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.