Evidence map›Paper›PMID 41103438›Full record

ArticleFrontiers in immunology2025

Case Report: Novel

Tingyan He, Junbin Ou, Lijuan Huang, Xinyi Zhou, Linlin Wang, Xiaolin Li, Jun Yang

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tingyan HeDepartment of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.
Junbin OuDepartment of Pediatric Rheumatology and Immunology, Boai Hospital of Zhongshan, Zhongshan, China.
Lijuan HuangDepartment of Pediatric Rheumatology and Immunology, Boai Hospital of Zhongshan, Zhongshan, China.
Xinyi ZhouDepartment of Pediatric Rheumatology and Immunology, Boai Hospital of Zhongshan, Zhongshan, China.
Linlin WangDepartment of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.
Xiaolin LiDepartment of Pediatric Rheumatology and Immunology, Boai Hospital of Zhongshan, Zhongshan, China.
Jun YangDepartment of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: UNC93B1 is a transmembrane protein essential for regulating toll-like receptors (TLRs). Pathogenic variants in human Methods: Demographic data, medical history, and physical examination findings were obtained. Whole-exome sequencing and Sanger sequencing were performed. The interferon-stimulated gene (ISG) score was analyzed. Results: We report four patients with a novel Conclusion:

Indexed as

Arthritis, RheumatoidLung Diseases, InterstitialMembrane Transport ProteinsMutationExome SequencingGenetic Predisposition to DiseaseHumansMembrane Transport ProteinsUNC93B1 protein, humanarthritisautoimmune diseasemonogenic lupussystemic lupus erythematosusUNC93B1

Identifiers

PMID41103438
PMCPMC12521461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.