Evidence map›Paper›PMID 41103344›Full record

Trial reportJournal of diabetes research2025

Differential Effects of Aerobic, Resistance, and Combined Trainings on First- and Second-Phase Insulin Secretion and Glucose Effectiveness in Type 2 Diabetes: A Randomized Controlled Trial.

Elaheh Piralaiy, Alireza Rashidpour, Badrkhan Rashwan Ismael

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elaheh PiralaiyDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.ORCID https://orcid.org/0000-0002-9201-7170
Alireza RashidpourDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.ORCID https://orcid.org/0000-0001-5575-3032
Badrkhan Rashwan IsmaelDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.ORCID https://orcid.org/0009-0006-2832-9854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This randomized controlled trial evaluated the differential effects of aerobic training (AT), resistance training (RT), and combined training (CT) on biphasic insulin secretion and glucose effectiveness (GE) in patients with Type 2 diabetes mellitus (T2DM). Methods: Forty-five male T2DM patients (mean age: 55.24 ± 8.17 years; disease duration: 12.51 ± 6.46 years; baseline HbA1c: 7.1% ± 1.0%) were randomized to 12-week AT ( Results: Adjusting for baseline values, age, and diabetes duration, ANCOVA revealed significant between-group differences in FPIS ( Conclusions: CT outperforms single-modality training in enhancing biphasic insulin secretion and GE in T2DM, supporting multimodal exercise as a cornerstone of diabetes management to improve Trial Registration: ClinicalTrials.gov identifier: IRCT2016042227529N1.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2ExerciseExercise TherapyInsulinInsulin SecretionResistance TrainingAdultAgedGlycated HemoglobinHumansMaleMiddle AgedTreatment OutcomeBlood GlucoseGlycated HemoglobinInsulinbeta-cell functioncombined exerciseexercise trainingglucose effectivenessinsulin secretionType 2 diabetes

Identifiers

PMID41103344
PMCPMC12527604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.