Evidence map›Paper›PMID 41103319›Full record

ArticleFrontiers in nutrition2025

Impact of using supplemented thylakoids derived from spinach for 12 weeks of high-intensity functional training on adipo-myokines in obese males.

Asieh Abbassi-Daloii, Maha Hoteit, Zahra Sadek, Mahboubeh Khak-Rand, Akbar Ramezani, Zhaleh Pashaei, Mahsa Afshar, Kurt A Escobar, Rashmi Supriya, Ayoub Saeidi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Asieh Abbassi-DaloiiDepartment of Exercise Physiology, Am.C., Islamic Azad University, Amol, Iran.
Maha HoteitPHENOL Research Group (Public Health Nutrition Program Lebanon), Faculty of Public Health, Lebanese University, Beirut, Lebanon.
Zahra SadekFaculty of Public Health, Section I, Lebanese University, Beirut, Lebanon.
Mahboubeh Khak-RandDepartment of Exercise Physiology, Am.C., Islamic Azad University, Amol, Iran.
Akbar RamezaniDepartment of Exercise Physiology, Am.C., Islamic Azad University, Amol, Iran.
Zhaleh PashaeiDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.
Mahsa AfsharDepartment of Physical Education, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Kurt A EscobarDepartment of Kinesiology, California State University, Long Beach, CA, United States.
Rashmi SupriyaCentre for Health and Exercise Science Research, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, China.
Ayoub SaeidiDepartment of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.
Hassane ZouhalInternational Institute of Sport Sciences (2I2S), Irodouer, France.
Ahmad AlkhatibDepartment of Life and Sport Sciences, School of Health and Life Sciences, Birmingham City University, Birmingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This randomized controlled study investigated the independent and combined effects of High-Intensity Functional Training (HIFT) and spinach-derived thylakoid supplementation on adipo-myokines, glycemic control, and lipid profiles in obese males. To compare the effects of HIFT alone, thylakoid supplementation (Thyl) alone, and their combination (HIFT+Thyl) on circulating adipokines (CTRP-2, CTRP-9, GDF-8, GDF-15), insulin resistance, and lipid profiles in obese adult males. Methods: A total of 68 participants who were obese with BMI: 32.6 ± 2.6 kg/m2 were randomly assigned to four groups ( Results: There were significant group × time interactions for all variables (all Conclusion: These findings indicate that HIFT combined with spinach-derived thylakoid supplementation significantly decreases circulating adipo-myokines and improves insulin resistance and lipid profiles in obese adults, suggesting a promising lifestyle intervention for obesity management and cardiometabolic disease prevention. Further research is warranted to explore long-term effects and underlying mechanisms. Clinical Trial Registration: https://irct.behdasht.gov.ir/trial/69048, identifier (IRCT20151228025732N77).

Indexed as

adipokineshigh-intensity functional traininginsulin resistanceobesityspinach-derived thylakoid

Identifiers

PMID41103319
PMCPMC12520950

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.