Evidence map›Paper›PMID 41103211›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

TVB C++: A Fast and Flexible Back-End for The Virtual Brain.

Ignacio Martín, Gorka Zamora-López, Jan Fousek, Michael Schirner, Petra Ritter, Viktor Jirsa, Gustavo Deco, Gustavo Patow

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. TVB C++: A Fast and Flexible Back-End for The Virtual Brain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ignacio MartínViRVIG, Universitat de Girona, Girona, 17003, Spain.
Gorka Zamora-LópezCenter for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, 08005, Spain.
Jan FousekInstitut de Neurosciences des Systèmes, Aix Marseille Université, Marseille, 13005, France.
Michael SchirnerBerlin Institute of Health, Charité - Universitätsmedizin Berlin, 10178, Berlin, Germany.
Petra RitterBerlin Institute of Health, Charité - Universitätsmedizin Berlin, 10178, Berlin, Germany.
Viktor JirsaInstitut de Neurosciences des Systèmes, Aix Marseille Université, Marseille, 13005, France.
Gustavo DecoCenter for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, 08005, Spain.
Gustavo PatowViRVIG, Universitat de Girona, Girona, 17003, Spain.ORCID https://orcid.org/0000-0002-1977-9101

Funding

AGAUR 2021SGR00917AGAUR 2021SGR01035Agence Nationale de la Recherche ANR-22-PESN-0012DFG Clinical Research Group BECAUSE-Y 504745852ERDF CZ.02.01.01/00/22\_008/0004643European Research Council NEMESIS(101071900)German Research Foundation 178316478German Research Foundation 327654276German Research Foundation 424778381German Research Foundation 425899996H2020 Excellent Science 785907 (HBP SGA2)Horizon 2020 945539(HBPSGA3)HORIZON EUROPE Framework Programme AISN - 101057655HORIZON EUROPE Framework Programme BRIDGE(101219311)HORIZON EUROPE Framework Programme CoordinaTEF(101168074)HORIZON EUROPE Framework Programme DigitalEuropeTEF-Health(101100700)HORIZON EUROPE Framework Programme EBRAIN-Health 101058516HORIZON EUROPE Framework Programme EBRAINS-PREP 101079717HORIZON EUROPE Framework Programme EICgrantPHRASE(101058240)HORIZON EUROPE Framework Programme Horizon EBRAINS2.0 (101147319)HORIZON EUROPE Framework Programme SHAIPED(101195135)HORIZON EUROPE Framework Programme Virtual Brain Twin (101137289)Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren RI 2073/10-2Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren RI 2073/9-1Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren SFB 1315 (project ID 327654276)Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren SFB 1436 (project ID 425899996)Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren SFB 936 (project ID 178316478Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren SFB-TRR 295 (project ID 424778381)Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren SPP Computational Connectomics RI 2073/6-1Ministerio de Ciencia, Innovación y Universidades PID2021-122136OB-C22Ministerio de Ciencia, Innovación y Universidades PID2022-136216NB-I00SPP Computational Connectomics RI2073/10-2SPP Computational Connectomics RI2073/6-1SPP Computational Connectomics RI2073/9-1
6 · The paper itself

Abstract

This study introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the flexibility and ease of use characteristic of the original TVB platform. Positioned as a complementary tool, TVB serves as a prototyping platform, whereas TVB C++ becomes indispensable when performance is paramount, particularly for large-scale simulations and leveraging advanced computation facilities like supercomputers. Developed as a TVB-compatible Back-End, TVB C++ seamlessly integrates with the original TVB implementation, facilitating effortless usage. Users can easily configure TVB C++ to execute the same code as in TVB but with enhanced performance and parallelism capabilities. As a consequence, TVB C++ will enable the widespread use of individualized models that will open the possibility of designed tailored solutions at the individual patient level.

Indexed as

BrainBrain-Computer InterfacesComputer SimulationSoftwareUser-Computer InterfaceHumansC++fastthe virtual brainwhole‐brain model

Identifiers

PMID41103211
PMCPMC12786347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.