Evidence map›Paper›PMID 41103067›Full record

ArticlePhysiological reports2025

Exploring upper airway and laryngeal resistance to noninvasive ventilation in healthy awake adults.

Anne Kristine Brekka, Maria Vollsæter, Zoe Fretheim-Kelly, Manel Lujan, Roy Miodini Nilsen, Hege Havstad Clemm, John-Helge Heimdal, Thomas Halvorsen, Ove Fondenes, Ola Drange Røksund and 1 more

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne Kristine BrekkaThoracic Department, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-3058-6156
Maria VollsæterDepartment of Paediatrics, Haukeland University Hospital, Bergen, Norway.
Zoe Fretheim-KellyDepartment of Paediatrics, Haukeland University Hospital, Bergen, Norway.
Manel LujanServei de Pneumologia, Parc Taulí Hospital Universitari, Sabadell, Spain.
Roy Miodini NilsenFaculty of Health and Social Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Hege Havstad ClemmDepartment of Paediatrics, Haukeland University Hospital, Bergen, Norway.
John-Helge HeimdalDepartment of Otolaryngology, Haukeland University Hospital, Bergen, Norway.
Thomas HalvorsenDepartment of Paediatrics, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-1471-0225
Ove FondenesThoracic Department, Haukeland University Hospital, Bergen, Norway.
Ola Drange RøksundFaculty of Health and Social Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Tiina Maarit AndersenThoracic Department, Haukeland University Hospital, Bergen, Norway.

Funding

The Norwegian Advisory Unit for Home Mechanical Ventilation, Thoracic Department, Haukeland University Hospital, Bergen, NorwayThe Western Norway Regional Health Authority F-12654The Western Norway Regional Health Authority F-12817-D10980
6 · The paper itself

Abstract

The interaction between anatomical structures, pressure, and airflow impacts the airway resistance. The airflow during noninvasive ventilation (NIV) relies on the upper airway and laryngeal patency. This study aimed to quantify the airflow resistance at these levels during NIV. In this cross-sectional study examining 10 healthy, awake adults, we established a NIV setup incorporating a continuous video-recorded transnasal laryngoscopy and simultaneous airway pressure measurement using a transducer positioned above and below the vocal folds. Airflow and mask pressure were recorded by a pneumotachograph at the mask. NIV was delivered with inspiratory positive pressure (IPAP)/expiratory positive pressure (EPAP) set to 10/4 and 15/4 cmH

Indexed as

Airway ResistanceLarynxNoninvasive VentilationAdultCross-Sectional StudiesFemaleHumansLaryngoscopyMaleMiddle AgedWakefulnessinduced laryngeal obstructionnoninvasive ventilationtranslaryngeal resistanceupper airway resistance

Identifiers

PMID41103067
PMCPMC12531353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.