Evidence map›Paper›PMID 41102946›Full record

ArticleACS chemical biology2025

Leveraging Vulnerabilities in Copper Trafficking for Synergistic Antifungal Activity.

Catherine A Denning-Jannace, Katherine J James, Carlos R Monteagudo, Grace R Sturrock, Amy T R Robison, Francesca A Vaccaro, Sophia A Kuhn, Michael C Fitzgerald, Katherine J Franz

Abstract read
In one paragraph

Article in ACS chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catherine A Denning-JannaceDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0003-1750-1197
Katherine J JamesDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0003-2112-1904
Carlos R MonteagudoDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0002-2132-1095
Grace R SturrockDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.
Amy T R RobisonDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.
Francesca A VaccaroDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0002-1167-6108
Sophia A KuhnDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.
Michael C FitzgeraldDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0002-6719-4722
Katherine J FranzDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0002-9015-0998

Funding

Elucidating the Molecular Basis of Cellular Metal Stress by using Mass Spectrometry-Based Proteomic MethodsR01GM145035 · NIGMS · DUKE UNIVERSITY · PI FITZGERALD, MICHAEL C, FRANZ, KATHERINE J. · 2022 to 2025
$2.1M
Predoctoral Training in Pharmacological Sciences (Resubmission)T32GM133332 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tija C. Jacob, Francisco Jose Schopfer · 2020 to 2026
$1.8M
Investigation of the role of CuZnSod1 in sensing Cu-deficient conditions in Candida albicansF32GM153029 · NIGMS · DUKE UNIVERSITY · PI VACCARO, FRANCESCA · 2024 to 2025
$148k
NIGMS NIH HHS F32 GM153029NIGMS NIH HHS R01 GM145035NIGMS NIH HHS T32 GM133332
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsCandida albicansChelating AgentsCopperMolybdenumAzolesDrug SynergismFungal ProteinsMicrobial Sensitivity TestsOxidative StressAntifungal AgentsAzolesChelating AgentsCopperFungal ProteinsMolybdenumtetrathiomolybdate

Identifiers

PMID41102946
PMCPMC12952562

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.