Evidence map›Paper›PMID 41102906›Full record

ArticleAIDS care2025

Interpersonal factors associated with depression symptom severity among PrEP-naïve pregnant women in South Africa: a mixed-methods analysis.

A Bhardwaj, M R Fertig, J N Githaiga, L Knight, A Paige, C O'Cleirigh, C Psaros, A M Stanton

Abstract read
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In one paragraph

Article in AIDS care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

A BhardwajDepartment of Psychological & Brain Sciences, Boston University, Boston, USA.
M R FertigDepartment of Psychological & Brain Sciences, Boston University, Boston, USA.
J N GithaigaDivision of Social and Behavioural Sciences, University of Cape Town, Cape Town, South Africa.
L KnightDivision of Social and Behavioural Sciences, University of Cape Town, Cape Town, South Africa.
A PaigeDepartment of Psychological & Brain Sciences, Boston University, Boston, USA.
C O'CleirighPsychiatry Department, Massachusetts General Hospital, Boston, USA.
C PsarosPsychiatry Department, Massachusetts General Hospital, Boston, USA.
A M StantonDepartment of Psychological & Brain Sciences, Boston University, Boston, USA.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Reducing psychological barriers to PrEP persistence among pregnant and postpartum women in Cape Town, South AfricaK23MH131438 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Amelia M. Stanton · 2022 to 2026
$933k
Patient-Oriented Substance Use/Smoking Cessation Research in HIV Treatment and PreventionK24DA062568 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Conall Michael O'Cleirigh · 2024 to 2026
$639k
NIAID NIH HHS P30 AI060354NIDA NIH HHS K24 DA062568NIMH NIH HHS K23 MH131438
6 · The paper itself

Abstract

Depression during pregnancy is linked to reduced use and adherence to pre-exposure prophylaxis (PrEP), increasing HIV risk. However, few studies explore how interpersonal factors shape depressive symptoms in pregnant women. We surveyed 110 pregnant women in Cape Town, South Africa, assessing depression and three interpersonal constructs: reproductive autonomy, dyadic trust, and relationship power. Participants had a mean age of 25.7 years and a mean gestational age of 29.3 weeks. In the multivariable model, decreased reproductive autonomy in decision-making remained a significant predictor of increased depression symptom severity (

Indexed as

DepressionHIV InfectionsInterpersonal RelationsPre-Exposure ProphylaxisPregnancy Complications, InfectiousPregnant PeopleAdultDecision MakingFemaleHumansInterviews as TopicMalePersonal AutonomyPregnancyQualitative ResearchSeverity of Illness IndexdepressionHIV preventionpregnancyPrEPReproductive healthSDG 3: Good health and WellbeingSDG 5: Gender EqualitySouth Africawomen

Identifiers

PMID41102906
PMCPMC13316833

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.