Evidence map›Paper›PMID 41102867›Full record

Trial reportObesity (Silver Spring, Md.)2026

Cost-Effectiveness of Two Iterations of a Community-Based Cardiovascular Disease Prevention Intervention.

Elena Andreyeva, Meredith L Graham, Galen D Eldridge, Sara C Folta, Miriam E Nelson, David Strogatz, Rebecca A Seguin-Fowler

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03059472 (Strong Hearts for New York), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03059472 nacompletednot on this map

Strong Hearts for New York: A Rural Community CVD Prevention Program

TypeinterventionalSponsorCornell UniversityRan2017 to 2019Enrolled182ConditionsHeart Disease, Cardiovascular Disease, Sedentary Lifestyle, OverweightArmsGroup 1 (Intervention), Group 2 (Delayed intervention)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena AndreyevaSchool of Public Health, Texas A&M University, College Station, Texas, USA.
Meredith L GrahamInstitute for Advancing Health Through Agriculture, Texas A&M AgriLife Research, Dallas, Texas, USA.
Galen D EldridgeInstitute for Advancing Health Through Agriculture, Texas A&M AgriLife Research, Dallas, Texas, USA.
Sara C FoltaFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Miriam E NelsonFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
David StrogatzBassett Research Institute, Cooperstown, New York, USA.
Rebecca A Seguin-FowlerInstitute for Advancing Health Through Agriculture, Texas A&M University System, Institute for Advancing Health Through Agriculture, Texas A&M AgriLife Research, College Station, Texas, USA.ORCID https://orcid.org/0000-0002-5115-2341

Funding

Strong Hearts_Healthy Communities_A Rural Community CVD Prevention ProgramR01HL120702 · NHLBI · CORNELL UNIVERSITY · PI SEGUIN-FOWLER, REBECCA ANNE · 2014 to 2017
$1.6M
National Institute of Food and Agriculture 1013938NHLBI NIH HHS R01 HL120702
6 · The paper itself

Abstract

objectiveThis study aimed to conduct cost analysis (CA) and cost-effectiveness analysis (CEA) of Strong Hearts, Healthy Communities (SHHC) implemented in two randomized trials.

methodsWomen with obesity or women who were sedentary with overweight who were ≥ 40 years old from rural medically underserved towns were randomized to SHHC intervention or control. CA calculated total and per participant costs and opportunity costs. CEA compared incremental costs to incremental outcome changes. Quality-adjusted life year (QALY) CEA compared incremental costs and effectiveness of a national SHHC intervention for a hypothetical cohort of 2.2 million women.

resultsSHHC-1.0 resource cost was $775/participant and SHHC-2.0 was $747. The incremental cost-effectiveness ratio from the payer's perspective for SHHC-1.0 was $346/kg weight loss and $187 and $155 for SHHC-2.0 at 24 and 48 weeks, respectively. Over a 10-year horizon, to avert QALYs lost, SHHC-1.0 was estimated to cost $238,271 from the societal perspective and $62,646 from the health care sector perspective. For SHHC-2.0, the corresponding numbers were $214,257 and $67,747 at 24 weeks and $94,395 and $11,341 at 48 weeks.

conclusionsSHHC-2.0 compared favorably to SHHC-1.0 and could be cost-effective for longer-term effects. Results can help guide policy makers' decisions on larger-scale community-based obesity and cardiovascular disease prevention interventions.

trial registrationClinicalTrials.gov identifier NCT03059472.

Indexed as

Cardiovascular DiseasesCommunity Health ServicesObesityAdultCost-Benefit AnalysisFemaleHumansMiddle AgedQuality-Adjusted Life YearsRural PopulationSedentary BehaviorWeight Losscardiovascular diseasecost analysiscost‐effectivenesseconomic evaluationruralwomen

Identifiers

PMID41102867
PMCPMC12704013

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.