Evidence map›Paper›PMID 41102860›Full record

ReviewImplementation science communications2025

Implementability of clinical practice guidelines: the review and development of a Comprehensive Framework for Guideline Implementability (CFGI).

Dongmei Zhong, Yimin Wu, Gregory A Aarons, Alison M Hutchinson, William Cw Wong, Sensen Lv, Zaiwei Song, Yanni Wu, David Makram Bishai, Ken Chen and 6 more

Abstract readReview
In one paragraph

Review in Implementation science communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dongmei ZhongDermatology Hospital, Southern Medical University, Guangzhou, China.
Yimin WuThe Second Clinical School of Medicine, Southern Medical University, Guangzhou, China.
Gregory A AaronsDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Alison M HutchinsonSchool of Nursing and Midwifery, Centre for Quality and Patient Safety Research, Institute for Health Transformation, Deakin University, Geelong, VIC, Australia.
William Cw WongDepartment of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Sensen LvThe Third Hospital of Xiamen, Xiamen, China.
Zaiwei SongDepartment of Pharmacy, Peking University Third Hospital, Beijing, China.
Yanni WuNanfang Hospital, Southern Medical University, Guangzhou, China.
David Makram BishaiSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Ken ChenDepartment of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Nan YangEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Yaolong ChenEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Zhaolan LiuCentre for Evidence-Based Chinese Medicine, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Lijiao YanInstitute of Basic Clinical Medicine of Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Pengxiang ZhouDepartment of Pharmacy, Peking University Third Hospital, Beijing, China.
Dong Roman XuDermatology Hospital, Southern Medical University, Guangzhou, China. romanxu@i.smu.edu.cn.ORCID http://orcid.org/0000-0001-7438-632X

Funding

National Natural Science Foundation of China (NSFC) 72304007Swiss Agency for Development and Cooperation 81067392
6 · The paper itself

Abstract

introductionWe define clinical practice guideline (CPGs) implementability as the characteristics of the guideline that reflect the extent to which it is likely to be adopted in clinical practice. Our objectives were to create a comprehensive and evidence-informed framework of guideline implementability (CFGI).

methodsA mixed-methods approach was used. Based on a systematic literature review of six databases as the foundation, the initial version of the CFGI was created, followed by external consultations to gather feedback and natural language processing tool-assisted classification to refine the framework. To get external validation of the CFGI from expert feedback at an international conference.

resultsFifteen studies related to guideline implementability were identified from the systematic Literature review. The first version of CFGI was compiled, including 6 domains. Feedback on the first version was received from 16 stakeholders, including clinicians, nurses, medical managers, and guideline methodologists, combined with natural language processing tool-assisted classification. The final version of the CFGI is comprised of 6 core domains, containing 21 constructs: (1) Scope and purpose; (2) Clarity and consistency of recommendations; (3) Development and evidence base; (4) Structure and Contents; (5) Development team and transparency; and (6) Implementation environment and tools. Twenty-nine experts participated in the external validation, and the results showed that CFGI had good rationality, importance, clarity, feasibility, and necessity.

conclusionsThe development of the CFGI provides a systematic theoretical basis for the development and implementation of future CPGs, which will help to enhance the implementability of guidelines and facilitate their promotion and application in different medical settings. Future research can further validate and apply the CFGI, explore its effectiveness and feasibility in actual operation.

Indexed as

CFGIClinical practice guidelineFrameworkImplementability

Identifiers

PMID41102860
PMCPMC12532944

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.