Evidence map›Paper›PMID 41102853›Full record

ReviewChinese medicine2025

Mechanistic insights into the multi-target anti-atherosclerotic actions of rhubarb: a traditional remedy revisited.

Feng-Jiao Hu, Yue-Ming Tang, Bin-Yue Hu, Feng-Ning Yang, Wei Jin, Yi-Fan Miao, Yun Lu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng-Jiao HuDepartment of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-Er-Qiao Road, Chengdu, 610072, Sichuan Province, People's Republic of China.
Yue-Ming TangSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Bin-Yue HuSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Feng-Ning YangSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Wei JinDepartment of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-Er-Qiao Road, Chengdu, 610072, Sichuan Province, People's Republic of China.
Yi-Fan MiaoDepartment of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-Er-Qiao Road, Chengdu, 610072, Sichuan Province, People's Republic of China. miaoyf@cdutcm.edu.cn.
Yun LuDepartment of Emergency Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-Er-Qiao Road, Chengdu, 610072, Sichuan Province, People's Republic of China. 0550@cdutcm.edu.cn.

Funding

Chengdu University of Traditional Chinese Medicine BSH2023004Health Commission of Chengdu WXLH202403067Provincial Famous Traditional Chinese Medicine Li Kang Inheritance Studio CRS2025035Sichuan Provincial Finance Department CJJ2021051
6 · The paper itself

Abstract

Atherosclerosis (AS), a chronic inflammatory vascular disease, underlies the pathogenesis of most cardiovascular disorders. Its pathologic features include endothelial damage, inflammatory response, lipid plaque formation and rupture, thrombosis, and arterial stenosis occlusion. Severe AS can lead to the development of stroke, myocardial infarction and other adverse outcomes. Therefore, it is essential to choose reliable and effective drugs to control or alleviate the deterioration of AS. Rhubarb is a kind of Chinese herb in the Polygonaceae family, with the scientific name of Rheum palmatum L. Numerous studies in recent years have confirmed that the Chinese herb rhubarb possesses a wide range of pharmacological activities against a variety of diseases, including inflammation, cancer, digestive disorders, and cardiovascular diseases. This paper focuses on the different pharmacological impacts and possible action mechanisms of the main active constituents of rhubarb (including anthraquinones, anthracenes, stilbenes, tannins, etc.) in the treatment of AS, providing useful references for the treatment of AS and innovative pharmaceutical development.

Indexed as

AtherosclerosisChemical constituentsPharmacological actionRhubarb

Identifiers

PMID41102853
PMCPMC12529792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.