Evidence map›Paper›PMID 41102642›Full record

ArticleInternational journal of emergency medicine2025

Emergency department point of care ultrasound utility in diagnosing infective endocarditis presenting as abdominal pain with bilateral iliac occlusion.

Elizabeth Ming Jing Tan, Yee Kent Liew, Zhi-Yang Darren Low, Helen Yuan Zhang, Ivan Si Yong Chua

Abstract read
In one paragraph

Article in International journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth Ming Jing TanDepartment of Emergency Medicine, Singapore General Hospital, 1 Outram Road, Singapore, 169608, Singapore. elizabeth.tan.m.j@singhealth.com.sg.
Yee Kent LiewMOH Holdings, Singapore, Singapore.
Zhi-Yang Darren LowDepartment of Emergency Medicine, Singapore General Hospital, 1 Outram Road, Singapore, 169608, Singapore.
Helen Yuan ZhangDepartment of Emergency Medicine, Singapore General Hospital, 1 Outram Road, Singapore, 169608, Singapore.
Ivan Si Yong ChuaDepartment of Emergency Medicine, Singapore General Hospital, 1 Outram Road, Singapore, 169608, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfective Endocarditis (IE) is a life threatening disease which is relatively rare especially in young healthy adults, and patients can rapidly deteriorate due to valvular insufficiency; however diagnosis can be challenging in the Emergency Department (ED). CASE PRESENTATION: We present a case of a 37 year old male who attended the ED with fever, diarrhoea and abdominal pain for one week. On arrival, he was febrile and tachycardic with right iliac fossa tenderness. Computed Tomography scan of the Abdomen and Pelvis revealed splenic and left kidney infarcts with bilateral iliac artery thrombi. Bedside Point Of Care Ultrasound (POCUS) showed a large Mitral Valve vegetation which supported the diagnosis of infective endocarditis with septic emboli. The patient was given intravenous antibiotics, crystalloids and antipyretics. He was urgently referred to Cardiology and Cardiothoracic surgeons for definitive surgical management, and was subsequently intubated due to worsening hypoxia from acute valvular insufficiency complicated by heart failure. The same night, he underwent emergency mitral valve replacement and embolectomy of bilateral iliac arteries. Blood cultures grew Group B Streptococcus. During his stay, he developed multiple mycotic pseudoaneurysms and a left insular cortex infarct as complications from the septic emboli.

conclusionsThis patient had an atypical presentation of infective endocarditis in the ED, and bedside POCUS was one of the keys to the diagnosis. Although infective endocarditis is rare, emergency physicians should be aware of the diagnosis and its potential complications, and consider it in prolonged fever without a clear source. Bedside POCUS can be a valuable first-line imaging tool in the ED to rule in the diagnosis of IE, and to look for complications as well as indications for surgical intervention. Further research needs to be done to look at the sensitivity and specificity of POCUS compared to routine Transthoracic Echocardiogram/ Transoesophageal Echocardiogram.

Identifiers

PMID41102642
PMCPMC12532848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.