Evidence map›Paper›PMID 41102410›Full record

ReviewNature chemical biology2025

Advances in integrating microbial metabolism with catalytic systems.

Stefania Gianolio, Arpita Mrigwani, Francesca Paradisi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Tackling the global plastic pollution crisis.National science review · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stefania Gianolio *Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland.
Arpita Mrigwani *Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland.
Francesca ParadisiDepartment of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland. francesca.paradisi@unibe.ch.ORCID http://orcid.org/0000-0003-1704-0642

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 200021-232199
6 · The paper itself

Abstract

Integrated catalytic systems that combine microbial metabolism with chemocatalysis, electrocatalysis, photocatalysis and biocatalysis are emerging as sustainable solutions for hybrid chemical-biosynthetic production and environmental remediation. By leveraging the strengths of engineered microbial cells and their metabolic pathways, along with synthetic catalysts, these hybrid systems use the unique benefits of each catalytic process to enable complex, efficient transformations, marking a notable advance over conventional methods. This Review highlights the progress in the assembly of hybrid catalytic systems and their application in a range of diverse fields. We examine the advantages of integrating chemocatalysts with whole-cell microorganisms, fabricating bioelectrochemical systems and microbial-photocatalytic integration. We also discuss how metabolic pathways can be harnessed for the sustainable production of higher-value products and pharmaceuticals and discuss how these hybrid systems can reduce costs, eliminate enzyme purification steps and facilitate multistep cascades.

Indexed as

BacteriaMetabolic EngineeringBiocatalysisCatalysisMetabolic Networks and Pathways

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.