Evidence map›Paper›PMID 41102370›Full record

ArticleNPJ digital medicine2025

Automated real-time assessment of intracranial hemorrhage detection AI using an ensembled monitoring model (EMM).

Zhongnan Fang, Andrew Johnston, Lina Y Cheuy, Hye Sun Na, Magdalini Paschali, Camila Gonzalez, Bonnie A Armstrong, Arogya Koirala, Derrick Laurel, Andrew Walker Campion and 3 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Explainable Knowledge-Guided Algorithm for Contrast Extravasation Detection on Computed Tomography.IEEE journal of translational engineering in health and medicine · 2026
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zhongnan FangDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA. zhongnan@stanford.edu.
Andrew JohnstonDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Lina Y CheuyDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Hye Sun NaDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Magdalini PaschaliDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Camila GonzalezDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Bonnie A ArmstrongDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Arogya KoiralaDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Derrick LaurelDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Andrew Walker CampionDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Michael IvDepartment of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Akshay S Chaudhari *Department of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
David B Larson *Department of Radiology, School of Medicine, Stanford University, Stanford, CA, 94304, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and unreliable AI predictions, which increases cognitive burden, reduces productivity, and potentially leads to misdiagnoses. To address these challenges, we introduce Ensembled Monitoring Model (EMM), a framework inspired by clinical consensus practices using multiple expert reviews. Designed specifically for black-box commercial AI products, EMM operates independently without requiring access to internal AI components or intermediate outputs, while still providing robust confidence measurements. Using intracranial hemorrhage detection as our test case on a large, diverse dataset of 2919 studies, we demonstrate that EMM can successfully categorize confidence in the AI-generated prediction, suggest appropriate actions, and help physicians recognize low confidence scenarios, ultimately reducing cognitive burden. Importantly, we provide key technical considerations and best practices for successfully translating EMM into clinical settings.

Identifiers

PMID41102370
PMCPMC12531331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.