Evidence map›Paper›PMID 41102208›Full record

ArticleNPJ microgravity2025

Heterogeneous and lateralized cervical vascular responses to a 7-day head-down tilt bed rest.

Fengxia Yu, Xia Ma, Yawen Liu, Rui Wang, Zixu Huang, Yiwen Wang, Jianxiong Zhang, Ruihua Dong, Peng-Gang Qiao, Wei Zheng and 3 more

Abstract read
In one paragraph

Article in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fengxia YuDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xia MaDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yawen LiuDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Rui WangDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zixu HuangNational Space Science Center, Chinese Academy of Sciences, Beijing, China.
Yiwen WangNational Space Science Center, Chinese Academy of Sciences, Beijing, China.
Jianxiong ZhangResearch Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Ruihua DongResearch Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Peng-Gang QiaoDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. qiaopenggang@sina.com.
Wei ZhengNational Space Science Center, Chinese Academy of Sciences, Beijing, China.
Linxue QianDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Pengling RenDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. yihan3469@126.com.
Zhenchang WangDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. cjr.wzhch@vip.163.com.

Funding

Beijing Hospital Authority Innovation Studio of Young Staff Funding Support No.202302Beijing Postdoctoral Research Foundation; the postdoctoral launch project of the Beijing Friendship Hospital, Capital Medical University No. yybsh2024002Beijing Scholar 2015 Zhenchang Wangthe Space Medical Experiment Project of the China Manned Space Program No. HYZHXMH01005
6 · The paper itself

Abstract

This study aimed to investigate cervical vessel hemodynamics during 7 days of -6° head-down tilt (HDT) bed rest (BR) and 5 days of recovery in 40 healthy males, focusing on bilateral analysis and dynamic temporal monitoring. Diameter, flow velocity, and blood flow volume (BFV) of bilateral common (CCAs), internal (ICAs), external carotid arteries and vertebral arteries (VAs) were measured at eight time points using ultrasound. Cervical vessels exhibited heterogeneous and lateralized responses. Left VA exhibited the most pronounced BFV and velocity fluctuations, with significant reductions during HDT and recovery to baseline post-HDT, while right VA remained stable. CCAs and ICAs had dynamic diameter and velocity changes, but stable BFVs. Left VA BFV reduction was significantly associated with right VA dominance, elevated heart rate, and increased mean arterial pressure at HDT 3 d. Despite stable total BFV, left VA BFV declined during BR, warranting further monitoring.

Identifiers

PMID41102208
PMCPMC12533258

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.